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375 results

Showing: 251 - 300 of 375 results

  6. Sctrans-PP

    Pooled Library
    #153101
    Purpose
    CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae
    Depositor
    Irina Borodina
    Article
    Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(
    Expression
    Yeast
    Species
    Saccharomyces cerevisiae
    Use
    CRISPR
    Available since
    Jan. 20, 2021
    Availability
    Academic Institutions and Nonprofits only

  7. KSHV Tiling Library

    Pooled Library
    #180272
    Purpose
    sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.
    Depositor
    Britt Glaunsinger
    Article
    Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.
    Expression
    Mammalian
    Species
    Kaposi’s sarcoma-associated herpes virus
    Use
    Lentiviral
    Available since
    Feb. 11, 2022
    Availability
    Academic Institutions and Nonprofits only

  8. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

    Pooled Library
    #138015
    Purpose
    This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.
    Depositor
    William Pu
    Article
    VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi
    Species
    Mus musculus
    Use
    AAV, CRISPR, and Cre/Lox
    Available since
    April 17, 2020
    Availability
    Academic Institutions and Nonprofits only

  13. Sabatini/Lander Lab Ras synthetic lethal candidate focused human sgRNA library in lentiCRISPRv1

    Pooled Library
    #92352
    Purpose
    contains 6,661 sgRNAs (comprising 499 intergenic control sgRNAs and 6,162 sgRNAs targeting 132 control and candidate Ras synthetic lethal genes at up to 50 sgRNAs per gene)
    Depositor
    David Sabatini, Eric Lander
    Article
    Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300
    Species
    Homo sapiens
    Available since
    June 7, 2017
    Availability
    Academic Institutions and Nonprofits only

  14. EFS-mTSG

    Pooled Library
    #113584
    Purpose
    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes
    Depositor
    Sidi Chen
    Article
    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:
    Expression
    Mammalian
    Use
    AAV, CRISPR, Lentiviral, and Luciferase
    Available since
    July 23, 2019
    Availability
    Academic Institutions and Nonprofits only

  32. Oxford Drosophila melanogaster Genome-wide CRISPR Library

    Pooled Library
    #64750
    Purpose
    A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).
    Depositor
    Ji-Long Liu
    Article
    Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-
    Expression
    Insect
    Species
    Drosophila melanogaster, Streptococcus pyogenes, and Synthetic
    Use
    CRISPR
    Available since
    March 7, 2016
    Availability
    Academic Institutions and Nonprofits only

  46. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

    Pooled Library
    #174296
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Article
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  47. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

    Pooled Library
    #174295
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Article
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  48. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

    Pooled Library
    #174294
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Article
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only

  49. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled Library
    #174293
    Purpose
    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.
    Depositor
    Timothy Whitehead
    Article
    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:
    Expression
    Yeast
    Available since
    Sept. 13, 2021
    Availability
    Academic Institutions and Nonprofits only
Showing: 251 - 300 of 375 results