61,345 results
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Plasmid#156576PurposeMammalian expression of secreted protein fused to Fc(DAPA)-Avi-6xHis.DepositorInsertLCN2 (LCN2 Human)
TagsFc(DAPA)-AviTag-6xHisExpressionMammalianMutationFc region of human IgG contains D265A and P329A m…PromoterCMV/SP6Available SinceAug. 5, 2022AvailabilityAcademic Institutions and Nonprofits only -
pTSHZ2-donor
Plasmid#113810PurposeCRISPR donor plasmid to tag human transcription factor TSHZ2 with GFPDepositorInsertTSHZ2 homology arms flanking EGFP-IRES-Neo cassette (TSHZ2 Human)
UseCRISPRAvailable SinceDec. 4, 2018AvailabilityAcademic Institutions and Nonprofits only -
STAG1-NanoLuc Vector
Plasmid#238688PurposeExpress STAG1-NanoLuc Fusion Protein in Mammalian Cells under a CMV promoterDepositorHas ServiceDNAInsertSTAG1 (STAG1 Human)
TagsNanoLuc (R)ExpressionMammalianMutationNonePromoterCMVAvailable SinceMarch 4, 2026AvailabilityIndustry, Academic Institutions, and Nonprofits -
pcDNA3.1(+)-N-DYK_K164R PCNA
Plasmid#221874PurposeExpresses K164R PCNA with a FLAG tag in mammalian cellsDepositorAvailable SinceFeb. 23, 2026AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1(+)-N-DYK_WT PCNA
Plasmid#221858PurposeExpresses WT PCNA with a FLAG tag in mammalian cellsDepositorAvailable SinceFeb. 23, 2026AvailabilityAcademic Institutions and Nonprofits only -
pLV-8xGTIIC-mScarlet-NLS-PEST
Plasmid#249724PurposeNuclear-localized fluorescent reporter of YAP/TAZ activity driven by promoter with TEAD binding sitesDepositorInsertYAP-TEAD responsive promoter (YAP1 Human)
UseLentiviralTagsmScarlet3-NLS-PESTExpressionMammalianAvailable SinceFeb. 20, 2026AvailabilityAcademic Institutions and Nonprofits only -
pACEBac1-eIF3b
Plasmid#240025PurposeHuman eIF3b for further cloning or expression in insect cells for purificationDepositorAvailable SinceJan. 7, 2026AvailabilityAcademic Institutions and Nonprofits only -
CL20_MSCV-NUP98::KDM5A-ires-GFP
Plasmid#237489PurposeExpress NUP98::KDM5A in bicistronic retroviral vectorDepositorAvailable SinceJune 30, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLIX401 C-term SETX
Plasmid#237999PurposeInducible lentiviral expression of C-term SETXDepositorAvailable SinceApril 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
pQCXIP-EGFP-APEX2-V5-EEA1
Plasmid#236403PurposeExpresses a fluorescent endosome-localized APEX2DepositorInsertEGFP-APEX2-V5-EEA1
UseRetroviralTagsAPEX2, EGFP, and V5ExpressionMammalianAvailable SinceApril 24, 2025AvailabilityAcademic Institutions and Nonprofits only -
A1-LCD D262V
Plasmid#234607PurposeBacterial expression of N-terminally 6His tagged hnRNPA1 D262V LCD (186-320)DepositorInserthnRNPA1_LCD_D262V (HNRNPA1 Human)
Tags6xHis-TEVExpressionBacterialMutationC-terminal domain (186-320) bearing familial ALS …PromoterT7Available SinceApril 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
A1-LCD D262N
Plasmid#234608PurposeBacterial expression of N-terminally 6His tagged hnRNPA1 D262N LCD (186-320)DepositorInserthnRNPA1_LCD_D262N (HNRNPA1 Human)
Tags6xHis-TEVExpressionBacterialMutationC-terminal domain (186-320) bearing familial ALS …PromoterT7Available SinceApril 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
pLentiCRISPRpuro-sgSEC24C #1
Plasmid#231563PurposepLentiCRISPR expression vector for Cas9 and gRNA targeting human SEC24C (#1) (Puromycin selection marker)DepositorAvailable SinceFeb. 3, 2025AvailabilityAcademic Institutions and Nonprofits only -
pMVP-SEC24C
Plasmid#231559PurposepMVP expression vector for human SEC24C (wild type, closed, resistant to sgSEC24C #1 and #2) (Blasticidin selection marker)DepositorInsertSEC24C (SEC24C Human)
UseLentiviralTagsV5ExpressionMammalianMutationsilent PAM mutations (G67 (GGG>GGA) and A115 (…PromoterCMVAvailable SinceJan. 30, 2025AvailabilityAcademic Institutions and Nonprofits only -
p5’UTR-ORF1
Plasmid#190566PurposeHolding vector containing the contiguous 5’UTR and ORF1 regions of human L1 (L1.3) to facilitate subcloning of ORF1 mutants into the full-length L1 reporter pRTC2-puro (Cook et al., 2015).DepositorInsertContiguous regions of the human L1 (L1.3) 5’UTR and ORF1
UseFor dna propagation onlyExpressionBacterialPromoterN/AAvailable SinceMay 16, 2023AvailabilityAcademic Institutions and Nonprofits only -
pD649-HAsp-LILRB5-Fc(DAPA)-AviTag-6xHis
Plasmid#156860PurposeMammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.DepositorInsertLILRB5 (LILRB5 Human)
TagsFc(DAPA)-AviTag-6xHisExpressionMammalianMutationFc region of human IgG contains D265A and P329A m…PromoterCMV/SP6Available SinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pTSHZ2.1.0-gDNA
Plasmid#113778PurposeCRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor TSHZ2DepositorAvailable SinceDec. 11, 2018AvailabilityAcademic Institutions and Nonprofits only -
pMRX-IP-TMEM192-mKeima
Plasmid#215358PurposeProbe to evaluate lysophagic activityDepositorAvailable SinceApril 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pTMB352_ZFcharm_Kv1_split-inteins
Plasmid#220848PurposeLentiviral vector expressing ZFcharm Kv2 fused to ZF3 and MmZFP_81187 via split Npu inteins; perfect match ZF3 binding site located upstream of pEFSDepositorInsertZFcharm Kv2
UseLentiviralTagsP2A-mCherryExpressionMammalianMutationN/APromoterEFSAvailable SinceJune 25, 2024AvailabilityAcademic Institutions and Nonprofits only -
Ubiquitin G76C
Plasmid#86583PurposeBacterial expression of Ubiquitin G76C for cross linking studiesDepositorInsertUbiquitin (UBC Human)
TagsHis6-MBPExpressionBacterialMutationTEV site; G76CPromoterTacAvailable SinceFeb. 24, 2017AvailabilityIndustry, Academic Institutions, and Nonprofits -
AA0250-mCherry-2a-hM4D-nrxn1a rev
Plasmid#60544PurposeCo-expresses hM4Dnrxn and a red fluorescent label from a Cre-dependent virusDepositorInsertsUseAAV and Cre/LoxTags2xHAPromoterCAGAvailable SinceJan. 26, 2015AvailabilityAcademic Institutions and Nonprofits only -
TFORF1319
Plasmid#143490PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorAvailable SinceJuly 11, 2023AvailabilityAcademic Institutions and Nonprofits only -
pEGFPC1-hVAP-B
Plasmid#104448PurposeExpression of human VAP-B fused to GFP in mammalian cellsDepositorInsertvesicle-associated membrane protein-associated protein B (VAPB Human)
TagsEGFP and HAExpressionMammalianAvailable SinceMay 15, 2018AvailabilityAcademic Institutions and Nonprofits only -
MS2-P65-HSF1_GFP
Plasmid#61423PurposeExpresses the MS2-P65-HSF1 activator helper complex with a 2A GFP. 3rd generation lentiviral vector.DepositorInsertMS2(N55K)-P65-HSF1_2A_GFP (HSF1 Synthetic, Human)
UseCRISPR and LentiviralExpressionMammalianMutationN55K in MS2PromoterEF1AAvailable SinceDec. 15, 2014AvailabilityAcademic Institutions and Nonprofits only -
Flag-FOXD1
Plasmid#153116PurposeExpression of Flag tagged human FOXD1 in mammalian cellsDepositorAvailable SinceAug. 24, 2020AvailabilityAcademic Institutions and Nonprofits only -
CRBN_ΔHBD
Plasmid#232779PurposeExpresses CRBN_ΔHBD sequence in E. coli cells with cleavable MBP-His tag and deleted internal DDB1 binding domainDepositorInsertCereblon (CRBN Human)
TagsMBP-His6-TEVExpressionBacterialMutationCRBN (residues 47 to 193 and 249 to 436) with GNG…PromoterT7Available SinceFeb. 20, 2025AvailabilityAcademic Institutions and Nonprofits only -
PBAN-tetOn-NKX3.1
Plasmid#238472PurposeDoxycycline inducible expression of the NKX3.1 transcription factor for mural cell differentiation.DepositorInsertNKX3.1 (NKX3-1 Human)
ExpressionMammalianAvailable SinceOct. 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
hGli3 flag3x
Plasmid#84921Purposemammalian expression of Gli3DepositorAvailable SinceNov. 14, 2016AvailabilityAcademic Institutions and Nonprofits only -
pLV-EF1A-CD19.8H.8TM.BB.3z
Plasmid#200671PurposeModular CD8hinge-CD8transmembrane-41BB-CD3z CAR backbone, For Transient Expression or Lentiviral ProductionDepositorUseLentiviralTagsMycTagExpressionMammalianPromoterEF1a-shortAvailable SinceNov. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
TFORF3054
Plasmid#144530PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorAvailable SinceAug. 14, 2023AvailabilityAcademic Institutions and Nonprofits only -
TRUPATH Triple GaoA
Plasmid#196051PurposeEncodes a G alpha subunit (GNAO1 Isoform Alpha 1) with RLuc8, a G gamma subunit (GNG8) with GFP2 and a G beta subunit (GNB3) as optimal components of a BRET2 biosensorDepositorUseLuciferaseTagsGFP2 and GSAG linkerExpressionMammalianMutationRLuc8 and flanking SGGGGS linkers have been inser…PromoterCMVAvailable SinceFeb. 27, 2023AvailabilityAcademic Institutions and Nonprofits only -
p11d-tRPA(123)
Plasmid#102613PurposeExpression of human RPA in E. coliDepositorAvailable SinceNov. 7, 2017AvailabilityAcademic Institutions and Nonprofits only -
HA Depdc5 pRK5
Plasmid#46327DepositorInsertDepdc5 (DEPDC5 Human)
TagsHAExpressionMammalianMutationDiffers from Depdc5 isoform 1 by 10 amino acids …Available SinceJuly 16, 2013AvailabilityAcademic Institutions and Nonprofits only -
pEGFPN1-human Dynamin 1aa K44A
Plasmid#22197DepositorInserthuman Dynamin 1aa K44A (DNM1 Human)
TagsGFPExpressionBacterial and MammalianMutationK44AAvailable SinceNov. 2, 2009AvailabilityAcademic Institutions and Nonprofits only -
Human SERCA2b (pcDNA3.1+)
Plasmid#75188PurposeMammalian expression of ATP2A2DepositorAvailable SinceJune 21, 2016AvailabilityAcademic Institutions and Nonprofits only -
GFP-ZMYND8
Plasmid#65401PurposeGFP-tagged BRD protein, which can be used to be expressed in mammalian cells.DepositorAvailable SinceMay 13, 2015AvailabilityAcademic Institutions and Nonprofits only -
pEGFP-N1-TFE3
Plasmid#38120DepositorAvailable SinceJuly 16, 2012AvailabilityAcademic Institutions and Nonprofits only -
SPLICS LY-MT Long P2A
Plasmid#213613PurposeDetect the long-range Lysosome-Mitochondria contactDepositorInsertSPLICS LY-MT Long P2A
ExpressionMammalianAvailable SinceFeb. 20, 2024AvailabilityAcademic Institutions and Nonprofits only -
hUbc13
Plasmid#51131Purposehuman ubc13, E2 for synthesis k63 linked ubiquitin chainDepositorAvailable SinceJan. 29, 2015AvailabilityAcademic Institutions and Nonprofits only -
pHR-UCOE-SFFV-dCas9-mCherry-ZIM3-KRAB
Plasmid#154473PurposeExpresses dCas9 fused to mCherry and the KRAB domain of ZIM3DepositorInsertZIM3 (ZIM3 Human)
UseLentiviralTagsHAExpressionMammalianMutationIncludes ZIM3 aa 1-100PromoterSFFVAvailable SinceOct. 5, 2020AvailabilityAcademic Institutions and Nonprofits only -
EGFP-E-Syt1
Plasmid#66830PurposeMammalian Expression, Bacterial ExpressionDepositorAvailable SinceJune 22, 2015AvailabilityAcademic Institutions and Nonprofits only -
SMN2E7-Fluc-Nluc-reporter
Plasmid#221005PurposeTransiently express SMN2 dual luciferase reporter. Inclusion of E7 produces in-frame stop codon and Firefly luciferase only, while skipping produces both Firefly and Nanoluc. CMV promoter.DepositorInsertFluc-SMN2E7-STOP-Nluc
ExpressionMammalianPromoterCMVAvailable SinceJune 24, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GRAB_ACh3.0
Plasmid#121922Purposeexpress the genetically-encoded fluorescent acethycholine(ACh) sensor GRAB-ACh3.0DepositorHas ServiceAAV9InsertGPCR activation based ACh sensor GRAB-ACh3.0
UseAAVPromoterhSynAvailable SinceJan. 16, 2020AvailabilityAcademic Institutions and Nonprofits only -
PRK5-FLAG-Bag6ΔUBL
Plasmid#61837Purposeexpress N-terminally FLAG tagged human Bag6 without UBL domainDepositorAvailable SinceSept. 2, 2016AvailabilityAcademic Institutions and Nonprofits only -
TRUPATH Triple Gaq
Plasmid#196058PurposeEncodes a G alpha subunit (GNAQ) with RLuc8, a G gamma subunit (GNG9) with GFP2 and a G beta subunit (GNB3) as optimal components of a BRET2 biosensor for studying heterotrimeric G proteinsDepositorUseLuciferaseTagsGFP2 and GSAG linkerExpressionMammalianMutationRLuc8 and flanking SGGGGS linkers have been inser…PromoterCMVAvailable SinceFeb. 27, 2023AvailabilityAcademic Institutions and Nonprofits only -
p300 core-dCas9-CBP core
Plasmid#179559Purposeencodes S. pyogenes dCas9 with n-terminal fusion of human p300 core (aa 1048-1664) and c-terminal fusion of human CBP core (aa 1084-1701) driven by EF-1alpha promoterDepositorInsertUseLentiviralTagsFlag TagExpressionMammalianMutationD10A; H840A in S.pyogenes Cas9PromoterEF-1alphaAvailable SinceFeb. 18, 2022AvailabilityAcademic Institutions and Nonprofits only -
TFORF2154
Plasmid#141947PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorAvailable SinceJan. 5, 2023AvailabilityAcademic Institutions and Nonprofits only -
pSV Sport RXR alpha
Plasmid#8882DepositorInsertRXR alpha (RXRA Human)
ExpressionMammalianAvailable SinceJan. 5, 2006AvailabilityAcademic Institutions and Nonprofits only -
pXJ-Myc-IRF1
Plasmid#232641Purposetransient expresses IRF1 in mammalian cellsDepositorAvailable SinceMarch 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
TRPC3-Myc
Plasmid#25902DepositorAvailable SinceJuly 14, 2014AvailabilityAcademic Institutions and Nonprofits only