Purpose
An engineered adenine transversion base editor (AYBEv3, A-to-C and/or A-to-T base editor) driven by EF1a promoter, guide RNAs compatible with spCas9 driven by hU6, mCherry driven by CBh promoter
Insert
ecTadA8e-nSpCas9(D10A)-MPG(v3)
Mutation
G163R, N169S, S198A, K202A, G203A, S206A, K210A
Available Since
Jan. 11, 2023
Availability
Academic Institutions and Nonprofits only