165,307 results

1. CIRC-V1-Ana-CVB3 IRES-EGFP-BbsI

   Plasmid

   #246754

   Purpose

   RNA circularization with CIRC using Ana intron, harbouring an CVB3 IRES-EGFP reporter.Plasmid was linearized with BbsI.

   Depositor

   Wensheng Wei

   Article

   Shen et al Nat Commun. 2025 Aug 10;16(1):7376. doi:

   Insert

   CIRC-V1-Ana-CVB3 IRES-EGFP-BbsI
   

   Use

   Synthetic Biology

   Available Since

   Oct. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pRedCas9

   Plasmid

   #240153

   Purpose

   Expresses lambda red machinery and cas9

   Depositor

   Morten Norholm

   Article

   Gude et al bioRxiv 2025.06.19.660532

   Inserts

   gam
   beta
   exo
   cas9
   

   Use

   CRISPR

   Expression

   Bacterial

   Available Since

   Oct. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCut_GFP

   Plasmid

   #240154

   Purpose

   Expresses CRISPR guides

   Depositor

   Morten Norholm

   Article

   Gude et al bioRxiv 2025.06.19.660532

   Inserts

   constant cut sites CRISPR guide array
   "self-curing" CRISPR guide array
   GFP
   

   Use

   CRISPR

   Expression

   Bacterial

   Available Since

   Oct. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pI-CreIAraRed_SC101_Spec

   Plasmid

   #240155

   Purpose

   Expresses lambda red machinery and i-creI

   Depositor

   Morten Norholm

   Article

   Gude et al bioRxiv 2025.06.19.660532

   Inserts

   gam
   beta
   exo
   i-creI
   

   Expression

   Bacterial

   Available Since

   Oct. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. hSyn1-DIO-mCherry-CAAX

   Plasmid

   #223673

   Purpose

   Cre-dependently expresses mCherry-CAAX in neurons

   Depositor

   Jun Nagai

   Article

   Dewa et al Nature. 2025 Oct 15. doi: 10.1038/s41586

   Insert

   mCherry-CAAX
   

   Use

   AAV and Cre/Lox

   Promoter

   hSyn1

   Available Since

   Oct. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. GfaABC1D-fDIO-mNeonGreen

   Plasmid

   #241240

   Purpose

   FRT-dependent expression of fluorescent protein, mNeonGreen, in astrocytes

   Depositor

   Jun Nagai

   Article

   Dewa et al Nature. 2025 Oct 15. doi: 10.1038/s41586

   Insert

   fDIO-mNeonGreen
   

   Use

   AAV

   Available Since

   Oct. 15, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. Phogrin mApple

   Plasmid

   #245045

   Purpose

   Secretory granule marker using Phogrin mApple as marker

   Depositor

   Thomas Martin

   Insert

   Phogrin (Ptprn2 Mouse)
   

   Tags

   mApple

   Expression

   Mammalian

   Available Since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. DCAF1-HaloTag Vector

   Plasmid

   #238664

   Purpose

   Express DCAF1-HaloTag Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   DCAF1 (DCAF1 Human)
   

   Tags

   HaloTag (R)

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CMV

   Available Since

   Sept. 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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9. 13xLexAop2 IVS sfGFP1-10

   Plasmid

   #221834

   Purpose

   Plasmid for generating 13xLexAop2 IVS sfGFP1-10 with attP/attB integration. It carries the attB sequence.

   Depositor

   Quentin Gaudry

   Article

   Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

   Insert

   sfGFP1-10
   

   Expression

   Insect

   Promoter

   hsp70

   Available Since

   Aug. 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pET21a asyn(14-140)

    Plasmid

    #240594

    Purpose

    Overexpress truncated alpha-Synuclein protein

    Depositor

    Jennifer Lee

    Article

    McGlinchey et al Proc Natl Acad Sci U S A. 2021 Aug 31;11

    Insert

    aSyn (SNCA Human)
    

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    aa 14-140 only

    Promoter

    T7

    Available Since

    Aug. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pET21a asyn(66-140)

    Plasmid

    #240582

    Purpose

    Overexpress truncated alpha-Synuclein protein

    Depositor

    Jennifer Lee

    Article

    McGlinchey et al Nat Commun. 2025 Apr 23;16(1):3825. doi:

    Insert

    aSyn (SNCA Human)
    

    Tags

    6xHis

    Expression

    Bacterial

    Mutation

    aa 66-140 only

    Promoter

    T7

    Available Since

    Aug. 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCAG-48xCCAT1 array

    Plasmid

    #236369

    Purpose

    Expression of array of 48 crRNAs targeting CCAT1

    Depositor

    Ling-Ling Chen

    Article

    Yang et al Nat Methods. 2024 Sep;21(9):1646-1657. d

    Insert

    48xCCAT1 crRNA array (CCAT1 Human)
    

    Use

    CRISPR and Lentiviral

    Available Since

    July 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pGEX4T-1 PDZD8-WT

    Plasmid

    #227849

    Purpose

    To express in E. coli PDZD8-WT

    Depositor

    Sheng-cai Lin

    Article

    Li et al Cell Res. 2024 Jun 19. doi: 10.1038/s414

    Insert

    PDZD8 (PDZD8 Human)
    

    Tags

    GST

    Expression

    Bacterial

    Available Since

    July 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. mScarlet-LRRK1 K746G

    Plasmid

    #233586

    Purpose

    Expresses LRRK1 K746G in mammalian cells

    Depositor

    Pietro De Camilli

    Article

    Wang et al Nat Cell Biol. 2025 May;27(5):776-789. d

    Insert

    LRRK1 K746G (LRRK1 Human)
    

    Tags

    mScarlet

    Expression

    Mammalian

    Available Since

    June 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pET-28c-F30-2xdBroccoli-47CAG

    Plasmid

    #237217

    Purpose

    Express F30-2xdBroccoli tagged 47 repeats of CAG RNA in bacteria.

    Depositor

    Mingxu You

    Article

    Xue et al Nucleic Acids Res. 2023 Sep 8;51(16):833

    Insert

    47 CAG trinucleotide repeats RNA
    

    Expression

    Bacterial

    Available Since

    June 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. Untagged TDP-43

    Plasmid

    #237551

    Purpose

    Expression of untagged wild-type TDP-43

    Depositor

    Tatyana Shelkovnikova

    Insert

    TDP-43 WT (TARDBP Human)
    

    Expression

    Mammalian

    Mutation

    wild-type TDP-43

    Promoter

    CMV

    Available Since

    May 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. TFORF0781

    Plasmid

    #143730

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    ZNF93 (ZNF93 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. 10279-M30-663

    Plasmid

    #225663

    Purpose

    Lentivirus protein expression. Matched control construct for 8522-M31-663 (Addgene # 225661) gives basal expression from mCMVp for gating/thresholding

    Depositor

    Dominic Esposito

    Article

    Tang et al Stem Cell Reports. 2015 Jan 13;4(1):155-

    Insert

    dsCherry
    

    Use

    Lentiviral

    Promoter

    mCMVp

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLenti-HA-L2HGDH(opt)-FLAG

    Plasmid

    #230089

    Purpose

    expressing human L2HGDH

    Depositor

    Xingguo Zhu

    Article

    Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

    Insert

    L2HGDH (L2HGDH Human)
    

    Use

    Lentiviral

    Tags

    FLAG and HA

    Expression

    Mammalian

    Mutation

    Multiple wobble mutations

    Promoter

    CMV

    Available Since

    Jan. 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pPICZ A-Strep-Opa1 (SB251)

    Plasmid

    #227600

    Purpose

    Inducible expression of Strep-tagged Opa1 in Pichia pastoris

    Depositor

    Luke Chao

    Article

    Boopathy et al J Biol Chem. 2024 Aug 31:107740. doi: 10

    Insert

    OPA1 (OPA1 Human)
    

    Tags

    Twin-StrepTag

    Expression

    Yeast

    Mutation

    contains aa 253-960 only

    Promoter

    AOX1

    Available Since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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21. pDRF1 ymScarletI3_T2A_mTurquoise2

    Plasmid

    #219829

    Purpose

    equimolar expression of ymScarletI3 and mTurquoise2 in budding yeast

    Depositor

    Bas Teusink

    Article

    Botman et al bioRxiv 2025.06.27.661975; doi: https://

    Insert

    ymScarletI3_T2A_mTurquoise2
    

    Expression

    Yeast

    Available Since

    Aug. 27, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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22. CCM2(FL)_pET49b

    Plasmid

    #224066

    Purpose

    Bacterial expression of full-length CCM2 fused to an N-terminal GST. HRV-3C cleavage site

    Depositor

    Ben Goult

    Article

    Ball et al J Cell Biol. 2024 Sep 2;223(9):e20231003

    Insert

    ccm2 (CCM2 Human)
    

    Tags

    GST; 6xHIS

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    Aug. 26, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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23. pTEF1_MS2

    Plasmid

    #220625

    Purpose

    Source for TEF1 MS2 coat fusion protein fusion

    Depositor

    Marvin Wickens

    Article

    Preston et al Nat Methods. 2019 May;16(5):437-445. doi

    Type

    Empty backbone

    Expression

    Yeast

    Available Since

    June 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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24. pL6-H2B-iRFP720-bla

    Plasmid

    #189991

    Purpose

    Lentivirial plasmid for nuclear iRFP-720 expression with blasticidin resistance

    Depositor

    Achim Kramer

    Article

    Gabriel et al Proc Natl Acad Sci U S A. 2024 Aug 20;12

    Insert

    Human histone H2B
    

    Use

    Lentiviral

    Tags

    iRFP720

    Expression

    Mammalian

    Available Since

    Feb. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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25. pMM7

    Plasmid

    #201213

    Purpose

    Integrative GFP-based shuttle vector for genetic engineering of Parageobacillus thermoglucosidasius. Carries homologous flanks for deletion of key sporulation regulator spo0A.

    Depositor

    Alex Nielsen

    Article

    Millgaard et al AMB Express. 2023 May 8;13(1):44. doi: 1

    Inserts

    sfGFP
    Spo0A right flank
    Spo0A left flank
    

    Use

    Synthetic Biology

    Expression

    Bacterial

    Mutation

    F11V, T13P, N39D, A179A

    Available Since

    Aug. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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26. TFORF2894

    Plasmid

    #144190

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    MTA1 (MTA1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Aug. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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27. ND6-L1397-N_UGI-NES_right

    Plasmid

    #187846

    Purpose

    expresses the right-side half ND6-UGI-NES in mammalian cells

    Depositor

    Chengqi Yi

    Article

    Lei et al Nature. 2022 May 12. pii: 10.1038/s41586

    Insert

    COX8A MTS–3xFLAG–ND6 right TALE–G1397 DddA-C–UGI–NES–ATP5B 3'UTR
    

    Expression

    Mammalian

    Available Since

    Oct. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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28. ND6-L1397-N_UGI-NES_left

    Plasmid

    #187845

    Purpose

    expresses the left-side half ND6-UGI-NES in mammalian cells

    Depositor

    Chengqi Yi

    Article

    Lei et al Nature. 2022 May 12. pii: 10.1038/s41586

    Insert

    SOD2 MTS–3x-HA–ND6 left tale–G1397 DddA-N–UGI–hivNES–SOD2 3'UTR
    

    Expression

    Mammalian

    Available Since

    Oct. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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29. pRS416-PTEF1-MCP-no_intron

    Plasmid

    #127597

    Purpose

    low-copy URA-selectable plasmid, 1xFLAG-MCP under TEF1 promoter

    Depositor

    David Bartel

    Article

    Morgan et al Nature. 2019 Jan;565(7741):606-611. doi:

    Insert

    1xFLAG-MCP expression cassette
    

    Expression

    Yeast

    Available Since

    April 9, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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30. pET28a(+)/FbGH17B

    Plasmid

    #100912

    Purpose

    Expression of the Beta-1,3-Exo-Laminarinase FbGH17B in E.coli

    Depositor

    Jan-Hendrik Hehemann

    Insert

    FbGH17Bcat
    

    Tags

    His-Tag

    Expression

    Bacterial

    Mutation

    not full length

    Available Since

    April 1, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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