lenti MS2-P65-HSF1_Hygro Citations (117)
Originally described in: Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F Nature. 2014 Dec 10. doi: 10.1038/nature14136. PubMed Journal
Articles Citing lenti MS2-P65-HSF1_Hygro
| Articles |
|---|
| Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease. Dahlman JE, Abudayyeh OO, Joung J, Gootenberg JS, Zhang F, Konermann S. Nat Biotechnol. 2015 Oct 5;33(11):1159-1161. doi: 10.1038/nbt.3390. PubMed |
| CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs. Zhang Y, Yin C, Zhang T, Li F, Yang W, Kaminski R, Fagan PR, Putatunda R, Young WB, Khalili K, Hu W. Sci Rep. 2015 Nov 5;5:16277. doi: 10.1038/srep16277. PubMed |
| Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex. Saayman SM, Lazar DC, Scott TA, Hart JR, Takahashi M, Burnett JC, Planelles V, Morris KV, Weinberg MS. Mol Ther. 2015 Nov 19. doi: 10.1038/mt.2015.202. PubMed |
| CRISPR-mediated Activation of Latent HIV-1 Expression. Limsirichai P, Gaj T, Schaffer DV. Mol Ther. 2015 Nov 26. doi: 10.1038/mt.2015.213. PubMed |
| Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators. Bogerd HP, Kornepati AV, Marshall JB, Kennedy EM, Cullen BR. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7249-56. doi: 10.1073/pnas.1516305112. Epub 2015 Dec 14. PubMed |
| Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Kennedy EM, Bogerd HP, Kornepati AV, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR. Cell Host Microbe. 2016 May 11;19(5):675-85. doi: 10.1016/j.chom.2016.04.002. Epub 2016 Apr 21. PubMed |
Comparison of Cas9 activators in multiple species.
Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G.
Nat Methods. 2016 May 23. doi: 10.1038/nmeth.3871.
PubMed
Associated Plasmids |
| Regulation of PCGEM1 by p54/nrb in prostate cancer. Ho TT, Huang J, Zhou N, Zhang Z, Koirala P, Zhou X, Wu F, Ding X, Mo YY. Sci Rep. 2016 Sep 29;6:34529. doi: 10.1038/srep34529. PubMed |
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library.
Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu XS, Wei W.
Nat Biotechnol. 2016 Dec;34(12):1279-1286. doi: 10.1038/nbt.3715. Epub 2016 Oct 31.
PubMed
Associated Plasmids |
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.
Hess GT, Fresard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC.
Nat Methods. 2016 Oct 31. doi: 10.1038/nmeth.4038.
PubMed
Associated Plasmids |
| Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM). Xiong K, Zhou Y, Hyttel P, Bolund L, Freude KK, Luo Y. Stem Cell Res. 2016 Nov 17;17(3):665-669. doi: 10.1016/j.scr.2016.10.011. PubMed |
Rewiring human cellular input-output using modular extracellular sensors.
Schwarz KA, Daringer NM, Dolberg TB, Leonard JN.
Nat Chem Biol. 2016 Dec 12. doi: 10.1038/nchembio.2253.
PubMed
Associated Plasmids |
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening.
Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F.
Nat Protoc. 2017 Apr;12(4):828-863. doi: 10.1038/nprot.2017.016. Epub 2017 Mar 23.
PubMed
Associated Plasmids |
| The Effects of Voluntary Physical Exercise-Activated Neurotrophic Signaling in Rat Hippocampus on mRNA Levels of Downstream Signaling Molecules. Solvsten CAE, Daugaard TF, Luo Y, de Paoli F, Christensen JH, Nielsen AL. J Mol Neurosci. 2017 Jun;62(2):142-153. doi: 10.1007/s12031-017-0918-9. Epub 2017 Apr 24. PubMed |
| A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, Helenius K, Park Y, Azimi R, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz OH, Xue W, Katajisto P, Bhutkar A, Jacks T. Nature. 2017 May 18;545(7654):355-359. doi: 10.1038/nature22334. Epub 2017 May 10. PubMed |
| Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Gocheva V, Naba A, Bhutkar A, Guardia T, Miller KM, Li CM, Dayton TL, Sanchez-Rivera FJ, Kim-Kiselak C, Jailkhani N, Winslow MM, Del Rosario A, Hynes RO, Jacks T. Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5625-E5634. doi: 10.1073/pnas.1707054114. Epub 2017 Jun 26. PubMed |
| EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas. Nowicki-Osuch K, Li Y, Challinor M, Gerrard DT, Hanley NA, Sharrocks AD. PLoS One. 2017 Jul 21;12(7):e0181902. doi: 10.1371/journal.pone.0181902. eCollection 2017. PubMed |
Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.
Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ.
Stem Cell Reports. 2017 Aug 8;9(2):615-628. doi: 10.1016/j.stemcr.2017.06.012. Epub 2017 Jul 27.
PubMed
Associated Plasmids |
| Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Nature. 2017 Aug 11. doi: 10.1038/nature23451. PubMed |
| Optimized strategy for in vivo Cas9-activation in Drosophila. Ewen-Campen B, Yang-Zhou D, Fernandes VR, Gonzalez DP, Liu LP, Tao R, Ren X, Sun J, Hu Y, Zirin J, Mohr SE, Ni JQ, Perrimon N. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9409-9414. doi: 10.1073/pnas.1707635114. Epub 2017 Aug 14. PubMed |
| Specific Expression of Interferon-gamma Induced by Synergistic Activation Mediator-Derived Systems Activates Innate Immunity and Inhibits Tumorigenesis. Liu S, Yu X, Wang Q, Liu Z, Xiao Q, Hou P, Hu Y, Hou W, Yang Z, Guo D, Chen S. J Microbiol Biotechnol. 2017 Oct 28;27(10):1855-1866. doi: 10.4014/jmb.1705.05081. PubMed |
One-Step piggyBac Transposon-Based CRISPR/Cas9 Activation of Multiple Genes.
Li S, Zhang A, Xue H, Li D, Liu Y.
Mol Ther Nucleic Acids. 2017 Sep 15;8:64-76. doi: 10.1016/j.omtn.2017.06.007. Epub 2017 Jun 15.
PubMed
Associated Plasmids |
| Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA. Lundh M, Plucinska K, Isidor MS, Petersen PSS, Emanuelli B. Mol Metab. 2017 Oct;6(10):1313-1320. doi: 10.1016/j.molmet.2017.07.001. Epub 2017 Jul 8. PubMed |
| Multiscale 3D Genome Rewiring during Mouse Neural Development. Bonev B, Mendelson Cohen N, Szabo Q, Fritsch L, Papadopoulos GL, Lubling Y, Xu X, Lv X, Hugnot JP, Tanay A, Cavalli G. Cell. 2017 Oct 19;171(3):557-572.e24. doi: 10.1016/j.cell.2017.09.043. PubMed |
| Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1. Kweon J, Jang AH, Kim DE, Yang JW, Yoon M, Rim Shin H, Kim JS, Kim Y. Nat Commun. 2017 Nov 23;8(1):1723. doi: 10.1038/s41467-017-01650-w. PubMed |
| Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families. Moretti AIS, Pavanelli JC, Nolasco P, Leisegang MS, Tanaka LY, Fernandes CG, Wosniak J Jr, Kajihara D, Dias MH, Fernandes DC, Jo H, Tran NV, Ebersberger I, Brandes RP, Bonatto D, Laurindo FRM. Sci Rep. 2017 Dec 8;7(1):17262. doi: 10.1038/s41598-017-16947-5. PubMed |
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.
Liao HK, Hatanaka F, Araoka T, Reddy P, Wu MZ, Sui Y, Yamauchi T, Sakurai M, O'Keefe DD, Nunez-Delicado E, Guillen P, Campistol JM, Wu CJ, Lu LF, Esteban CR, Izpisua Belmonte JC.
Cell. 2017 Dec 14;171(7):1495-1507.e15. doi: 10.1016/j.cell.2017.10.025. Epub 2017 Dec 7.
PubMed
Associated Plasmids |
Multimode drug inducible CRISPR/Cas9 devices for transcriptional activation and genome editing.
Lu J, Zhao C, Zhao Y, Zhang J, Zhang Y, Chen L, Han Q, Ying Y, Peng S, Ai R, Wang Y.
Nucleic Acids Res. 2018 Mar 16;46(5):e25. doi: 10.1093/nar/gkx1222.
PubMed
Associated Plasmids |
| Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes. Palau A, Garz AK, Diesch J, Zwick A, Malinverni R, Valero V, Lappin K, Casquero R, Lennartsson A, Zuber J, Navarro T, Mills KI, Gotze KS, Buschbeck M. Oncotarget. 2017 Dec 1;8(70):115002-115017. doi: 10.18632/oncotarget.22839. eCollection 2017 Dec 29. PubMed |
| RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells. Guallar D, Bi X, Pardavila JA, Huang X, Saenz C, Shi X, Zhou H, Faiola F, Ding J, Haruehanroengra P, Yang F, Li D, Sanchez-Priego C, Saunders A, Pan F, Valdes VJ, Kelley K, Blanco MG, Chen L, Wang H, Sheng J, Xu M, Fidalgo M, Shen X, Wang J. Nat Genet. 2018 Mar;50(3):443-451. doi: 10.1038/s41588-018-0060-9. Epub 2018 Feb 26. PubMed |
| TCF21/POD-1, a Transcritional Regulator of SF-1/NR5A1, as a Potential Prognosis Marker in Adult and Pediatric Adrenocortical Tumors. Passaia BDS, Dias MH, Kremer JL, Antonini SRR, de Almeida MQ, Fragoso MCBV, Lotfi CFP. Front Endocrinol (Lausanne). 2018 Feb 22;9:38. doi: 10.3389/fendo.2018.00038. eCollection 2018. PubMed |
| Simple method for assembly of CRISPR synergistic activation mediator gRNA expression array. Vad-Nielsen J, Nielsen AL, Luo Y. J Biotechnol. 2018 May 20;274:54-57. doi: 10.1016/j.jbiotec.2018.03.018. Epub 2018 Mar 26. PubMed |
| Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Jia Y, Xu RG, Ren X, Ewen-Campen B, Rajakumar R, Zirin J, Yang-Zhou D, Zhu R, Wang F, Mao D, Peng P, Qiao HH, Wang X, Liu LP, Xu B, Ji JY, Liu Q, Sun J, Perrimon N, Ni JQ. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4719-4724. doi: 10.1073/pnas.1800677115. Epub 2018 Apr 16. PubMed |
| An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP. Cell. 2018 Apr 19;173(3):649-664.e20. doi: 10.1016/j.cell.2018.03.052. PubMed |
| Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, Weissman JS, Curtis C, Chang HY. Cell. 2018 May 31;173(6):1398-1412.e22. doi: 10.1016/j.cell.2018.03.068. Epub 2018 May 3. PubMed |
Human pluripotent reprogramming with CRISPR activators.
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti EM, Trokovic R, Kere J, Otonkoski T.
Nat Commun. 2018 Jul 6;9(1):2643. doi: 10.1038/s41467-018-05067-x.
PubMed
Associated Plasmids |
| Comprehensive off-target analysis of dCas9-SAM-mediated HIV reactivation via long noncoding RNA and mRNA profiling. Zhang Y, Arango G, Li F, Xiao X, Putatunda R, Yu J, Yang XF, Wang H, Watson LT, Zhang L, Hu W. BMC Med Genomics. 2018 Sep 10;11(1):78. doi: 10.1186/s12920-018-0394-2. PubMed |
| Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Fauster A, Rebsamen M, Willmann KL, Cesar-Razquin A, Girardi E, Bigenzahn JW, Schischlik F, Scorzoni S, Bruckner M, Konecka J, Hormann K, Heinz LX, Boztug K, Superti-Furga G. Cell Death Differ. 2018 Sep 20. pii: 10.1038/s41418-018-0192-6. doi: 10.1038/s41418-018-0192-6. PubMed |
Intrinsic Nucleotide Preference of Diversifying Base Editors Guides Antibody Ex Vivo Affinity Maturation.
Liu LD, Huang M, Dai P, Liu T, Fan S, Cheng X, Zhao Y, Yeap LS, Meng FL.
Cell Rep. 2018 Oct 23;25(4):884-892.e3. doi: 10.1016/j.celrep.2018.09.090.
PubMed
Associated Plasmids |
| Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer. Zhang P, Kang B, Xie G, Li S, Gu Y, Shen Y, Zhao X, Ma Y, Li F, Si J, Wang J, Chen J, Yang H, Xu X, Yang Y. Cancer Lett. 2019 Feb 1;442:53-67. doi: 10.1016/j.canlet.2018.10.035. Epub 2018 Oct 27. PubMed |
Pooled extracellular receptor-ligand interaction screening using CRISPR activation.
Chong ZS, Ohnishi S, Yusa K, Wright GJ.
Genome Biol. 2018 Nov 26;19(1):205. doi: 10.1186/s13059-018-1581-3.
PubMed
Associated Plasmids |
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X.
Nat Neurosci. 2019 Mar;22(3):386-400. doi: 10.1038/s41593-019-0338-y. Epub 2019 Feb 11.
PubMed
Associated Plasmids |
| CRISPR-mediated activation of endogenous BST-2/tetherin expression inhibits wild-type HIV-1 production. Zhang Y, Ozono S, Yao W, Tobiume M, Yamaoka S, Kishigami S, Fujita H, Tokunaga K. Sci Rep. 2019 Feb 28;9(1):3134. doi: 10.1038/s41598-019-40003-z. PubMed |
| Optimization of lentiviral transduction parameters and its application for CRISPR-based secretome modification of human endometrial mesenchymal stem cells. Deryabin P, Griukova A, Shatrova A, Petukhov A, Nikolsky N, Borodkina A. Cell Cycle. 2019 Mar - Apr;18(6-7):742-758. doi: 10.1080/15384101.2019.1593650. Epub 2019 Mar 28. PubMed |
| PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression. Toska E, Castel P, Chhangawala S, Arruabarrena-Aristorena A, Chan C, Hristidis VC, Cocco E, Sallaku M, Xu G, Park J, Minuesa G, Shifman SG, Socci ND, Koche R, Leslie CS, Scaltriti M, Baselga J. Cell Rep. 2019 Apr 2;27(1):294-306.e5. doi: 10.1016/j.celrep.2019.02.111. PubMed |
| Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs. Pontis J, Planet E, Offner S, Turelli P, Duc J, Coudray A, Theunissen TW, Jaenisch R, Trono D. Cell Stem Cell. 2019 May 2;24(5):724-735.e5. doi: 10.1016/j.stem.2019.03.012. Epub 2019 Apr 18. PubMed |
| Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes. Hisano Y, Kono M, Cartier A, Engelbrecht E, Kano K, Kawakami K, Xiong Y, Piao W, Galvani S, Yanagida K, Kuo A, Ono Y, Ishida S, Aoki J, Proia RL, Bromberg JS, Inoue A, Hla T. J Exp Med. 2019 Jul 1;216(7):1582-1598. doi: 10.1084/jem.20181895. Epub 2019 May 30. PubMed |
| Reversible Regulation of Polyubiquitin Gene UBC via Modified Inducible CRISPR/Cas9 System. Han SW, Jung BK, Park SH, Ryu KY. Int J Mol Sci. 2019 Jun 28;20(13). pii: ijms20133168. doi: 10.3390/ijms20133168. PubMed |
| CRISPR/dCas9-mediated activation of multiple endogenous target genes directly converts human foreskin fibroblasts into Leydig-like cells. Huang H, Zou X, Zhong L, Hou Y, Zhou J, Zhang Z, Xing X, Sun J. J Cell Mol Med. 2019 Jul 2. doi: 10.1111/jcmm.14470. PubMed |
| Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium. Pentinmikko N, Iqbal S, Mana M, Andersson S, Cognetta AB 3rd, Suciu RM, Roper J, Luopajarvi K, Markelin E, Gopalakrishnan S, Smolander OP, Naranjo S, Saarinen T, Juuti A, Pietilainen K, Auvinen P, Ristimaki A, Gupta N, Tammela T, Jacks T, Sabatini DM, Cravatt BF, Yilmaz OH, Katajisto P. Nature. 2019 Jul;571(7765):398-402. doi: 10.1038/s41586-019-1383-0. Epub 2019 Jul 10. PubMed |
| Functional genomics identifies predictive markers and clinically actionable resistance mechanisms to CDK4/6 inhibition in bladder cancer. Tong Z, Sathe A, Ebner B, Qi P, Veltkamp C, Gschwend JE, Holm PS, Nawroth R. J Exp Clin Cancer Res. 2019 Jul 22;38(1):322. doi: 10.1186/s13046-019-1322-9. PubMed |
| MUC16 in non-small cell lung cancer patients affected by familial lung cancer and indoor air pollution: clinical characteristics and cell behaviors. Chen Y, Huang Y, Kanwal M, Li G, Yang J, Niu H, Li Z, Ding X. Transl Lung Cancer Res. 2019 Aug;8(4):476-488. doi: 10.21037/tlcr.2019.07.10. PubMed |
| H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling. Luo M, Bai J, Liu B, Yan P, Zuo F, Sun H, Sun Y, Xu X, Song Z, Yang Y, Massague J, Lan X, Lu Z, Chen YG, Deng H, Xie W, Xi Q. Stem Cell Reports. 2019 Oct 8;13(4):642-656. doi: 10.1016/j.stemcr.2019.08.016. Epub 2019 Sep 26. PubMed |
| Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer. Zhang Z, Lee JH, Ruan H, Ye Y, Krakowiak J, Hu Q, Xiang Y, Gong J, Zhou B, Wang L, Lin C, Diao L, Mills GB, Li W, Han L. Nat Commun. 2019 Oct 8;10(1):4562. doi: 10.1038/s41467-019-12543-5. PubMed |
| lncRNA RMST Enhances DNMT3 Expression through Interaction with HuR. Peng WX, Koirala P, Zhang W, Ni C, Wang Z, Yang L, Mo YY. Mol Ther. 2020 Jan 8;28(1):9-18. doi: 10.1016/j.ymthe.2019.09.024. Epub 2019 Oct 4. PubMed |
| Molecular basis of senescence transmitting in the population of human endometrial stromal cells. Griukova A, Deryabin P, Shatrova A, Burova E, Severino V, Farina A, Nikolsky N, Borodkina A. Aging (Albany NY). 2019 Nov 5;11(21):9912-9931. doi: 10.18632/aging.102441. Epub 2019 Nov 5. PubMed |
| A conserved miRNA-183 cluster regulates the innate antiviral response. Singaravelu R, Ahmed N, Quan C, Srinivasan P, Ablenas CJ, Roy DG, Pezacki JP. J Biol Chem. 2019 Dec 20;294(51):19785-19794. doi: 10.1074/jbc.RA119.010858. Epub 2019 Nov 6. PubMed |
| Distinct IL-1alpha-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner. Weiterer SS, Meier-Soelch J, Georgomanolis T, Mizi A, Beyerlein A, Weiser H, Brant L, Mayr-Buro C, Jurida L, Beuerlein K, Muller H, Weber A, Tenekeci U, Dittrich-Breiholz O, Bartkuhn M, Nist A, Stiewe T, van IJcken WF, Riedlinger T, Schmitz ML, Papantonis A, Kracht M. EMBO J. 2020 Jan 2;39(1):e101533. doi: 10.15252/embj.2019101533. Epub 2019 Nov 7. PubMed |
| Construction and optimization of a base editor based on the MS2 system. Zhang S, Feng S, Jiang W, Huang X, Chen J. Animal Model Exp Med. 2019 Sep 5;2(3):185-190. doi: 10.1002/ame2.12080. eCollection 2019 Sep. PubMed |
| The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status. Trigg RM, Lee LC, Prokoph N, Jahangiri L, Reynolds CP, Amos Burke GA, Probst NA, Han M, Matthews JD, Lim HK, Manners E, Martinez S, Pastor J, Blanco-Aparicio C, Merkel O, de Los Fayos Alonso IG, Kodajova P, Tangermann S, Hogler S, Luo J, Kenner L, Turner SD. Nat Commun. 2019 Nov 28;10(1):5428. doi: 10.1038/s41467-019-13315-x. PubMed |
| Gene activation by dCas9-CBP and the SAM system differ in target preference. Sajwan S, Mannervik M. Sci Rep. 2019 Dec 2;9(1):18104. doi: 10.1038/s41598-019-54179-x. PubMed |
| Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer. Deng X, Li S, Kong F, Ruan H, Xu X, Zhang X, Wu Z, Zhang L, Xu Y, Yuan H, Peng H, Yang D, Guan M. Theranostics. 2020 Jan 1;10(1):265-280. doi: 10.7150/thno.36045. eCollection 2020. PubMed |
| CRISPR-Cas9-induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expression. Roberston MJ, Raghunathan S, Potaman VN, Zhang F, Stewart MD, McConnell BK, Schwartz RJ. FASEB J. 2020 Jan;34(1):555-570. doi: 10.1096/fj.201901107RR. Epub 2019 Nov 25. PubMed |
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing.
Li K, Liu Y, Cao H, Zhang Y, Gu Z, Liu X, Yu A, Kaphle P, Dickerson KE, Ni M, Xu J.
Nat Commun. 2020 Jan 24;11(1):485. doi: 10.1038/s41467-020-14362-5.
PubMed
Associated Plasmids |
| Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma. Tian C, Ohlund D, Rickelt S, Lidstrom T, Huang Y, Hao L, Zhao RT, Franklin O, Bhatia SN, Tuveson DA, Hynes RO. Cancer Res. 2020 Apr 1;80(7):1461-1474. doi: 10.1158/0008-5472.CAN-19-2578. Epub 2020 Feb 6. PubMed |
| DUX-miR-344-ZMYM2-Mediated Activation of MERVL LTRs Induces a Totipotent 2C-like State. Yang F, Huang X, Zang R, Chen J, Fidalgo M, Sanchez-Priego C, Yang J, Caichen A, Ma F, Macfarlan T, Wang H, Gao S, Zhou H, Wang J. Cell Stem Cell. 2020 Feb 6;26(2):234-250.e7. doi: 10.1016/j.stem.2020.01.004. PubMed |
| Chromosome 19 microRNA cluster enhances cell reprogramming by inhibiting epithelial-to-mesenchymal transition. Mong EF, Yang Y, Akat KM, Canfield J, VanWye J, Lockhart J, Tsibris JCM, Schatz F, Lockwood CJ, Tuschl T, Kayisli UA, Totary-Jain H. Sci Rep. 2020 Feb 20;10(1):3029. doi: 10.1038/s41598-020-59812-8. PubMed |
| Lineage reprogramming of fibroblasts into induced cardiac progenitor cells by CRISPR/Cas9-based transcriptional activators. Wang J, Jiang X, Zhao L, Zuo S, Chen X, Zhang L, Lin Z, Zhao X, Qin Y, Zhou X, Yu XY. Acta Pharm Sin B. 2020 Feb;10(2):313-326. doi: 10.1016/j.apsb.2019.09.003. Epub 2019 Sep 17. PubMed |
| An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation. Raffeiner P, Hart JR, Garcia-Caballero D, Bar-Peled L, Weinberg MS, Vogt PK. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6571-6579. doi: 10.1073/pnas.1921786117. Epub 2020 Mar 10. PubMed |
| Leydig-like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats. Huang H, Zhong L, Zhou J, Hou Y, Zhang Z, Xing X, Sun J. J Cell Mol Med. 2020 Apr;24(7):3971-3981. doi: 10.1111/jcmm.15018. Epub 2020 Mar 11. PubMed |
| Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells. Petazzi P, Torres-Ruiz R, Fidanza A, Roca-Ho H, Gutierrez-Aguera F, Castano J, Rodriguez-Perales S, Diaz de la Guardia R, Lopez-Millan B, Bigas A, Forrester LM, Bueno C, Menendez P. Mol Ther Nucleic Acids. 2020 Jun 5;20:196-204. doi: 10.1016/j.omtn.2020.02.009. Epub 2020 Feb 27. PubMed |
| LRP6-CRISPR prevents activation of hepatic stellate cells and liver fibrogenesis in rats. Yu L, Wang L, Yi H, Wu X. Am J Transl Res. 2020 Feb 15;12(2):397-408. eCollection 2020. PubMed |
| A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells. Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, Fujita T, Fujii H, Liston A, Andrews S, Cozzani A, Yang J, Mitra S, Lugli E, Chang HY, Unutmaz D, Trynka G, Roychoudhuri R. Nature. 2020 Jul;583(7816):447-452. doi: 10.1038/s41586-020-2296-7. Epub 2020 May 13. PubMed |
| Enforced Activation of Enhancer RNAs In Situ through the dCas9 Synergistic Activation Mediator System. Liao Z, Lee JH, Krakowiak J, Wang R, Li W. J Vis Exp. 2020 Jun 5;(160). doi: 10.3791/61460. PubMed |
| Decipher the complexity of cis-regulatory regions by a modified Cas9. Kirchner S, Reuter S, Westphal A, Mrowka R. PLoS One. 2020 Jul 2;15(7):e0235530. doi: 10.1371/journal.pone.0235530. eCollection 2020. PubMed |
| Complex roles of the actin-binding protein Girdin/GIV in DNA damage-induced apoptosis of cancer cells. Chen C, Enomoto A, Weng L, Taki T, Shiraki Y, Mii S, Ichihara R, Kanda M, Koike M, Kodera Y, Takahashi M. Cancer Sci. 2020 Nov;111(11):4303-4317. doi: 10.1111/cas.14637. Epub 2020 Sep 19. PubMed |
| Gene Manipulation Using Fusion Guide RNAs for Cas9 and Cas12a. Shin HR, Kweon J, Kim Y. Methods Mol Biol. 2021;2162:185-193. doi: 10.1007/978-1-0716-0687-2_10. PubMed |
| Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors. Schleicher EM, Dhoonmoon A, Jackson LM, Clements KE, Stump CL, Nicolae CM, Moldovan GL. PLoS Genet. 2020 Nov 2;16(11):e1009176. doi: 10.1371/journal.pgen.1009176. eCollection 2020 Nov. PubMed |
| Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens. Clements KE, Schleicher EM, Thakar T, Hale A, Dhoonmoon A, Tolman NJ, Sharma A, Liang X, Imamura Kawasawa Y, Nicolae CM, Wang HG, De S, Moldovan GL. Nat Commun. 2020 Nov 30;11(1):6118. doi: 10.1038/s41467-020-19961-w. PubMed |
| SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression. Hou G, Harley ITW, Lu X, Zhou T, Xu N, Yao C, Qin Y, Ouyang Y, Ma J, Zhu X, Yu X, Xu H, Dai D, Ding H, Yin Z, Ye Z, Deng J, Zhou M, Tang Y, Namjou B, Guo Y, Weirauch MT, Kottyan LC, Harley JB, Shen N. Nat Commun. 2021 Jan 8;12(1):135. doi: 10.1038/s41467-020-20460-1. PubMed |
| The NFIB-ERO1A axis promotes breast cancer metastatic colonization of disseminated tumour cells. Zilli F, Marques Ramos P, Auf der Maur P, Jehanno C, Sethi A, Coissieux MM, Eichlisberger T, Sauteur L, Rouchon A, Bonapace L, Pinto Couto J, Rad R, Jensen MR, Banfi A, Stadler MB, Bentires-Alj M. EMBO Mol Med. 2021 Apr 9;13(4):e13162. doi: 10.15252/emmm.202013162. Epub 2021 Mar 10. PubMed |
| Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells. Tian C, Huang Y, Clauser KR, Rickelt S, Lau AN, Carr SA, Vander Heiden MG, Hynes RO. Nat Commun. 2021 Apr 20;12(1):2328. doi: 10.1038/s41467-021-22490-9. PubMed |
| Pooled CRISPR-activation screening coupled with single-cell RNA-seq in mouse embryonic stem cells. Alda-Catalinas C, Eckersley-Maslin MA, Reik W. STAR Protoc. 2021 Apr 9;2(2):100426. doi: 10.1016/j.xpro.2021.100426. eCollection 2021 Jun 18. PubMed |
| BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion. Perez-Garcia V, Lea G, Lopez-Jimenez P, Okkenhaug H, Burton GJ, Moffett A, Turco MY, Hemberger M. Elife. 2021 Jun 25;10. pii: 63254. doi: 10.7554/eLife.63254. PubMed |
| Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry. Zhu S, Liu Y, Zhou Z, Zhang Z, Xiao X, Liu Z, Chen A, Dong X, Tian F, Chen S, Xu Y, Wang C, Li Q, Niu X, Pan Q, Du S, Xiao J, Wang J, Wei W. Sci China Life Sci. 2022 Apr;65(4):701-717. doi: 10.1007/s11427-021-1990-5. Epub 2021 Aug 20. PubMed |
| AT-rich interaction domain 5A regulates the transcription of interleukin-6 gene in prostate cancer cells. Ikeuchi W, Wakita Y, Zhang G, Li C, Itakura K, Yamakawa T. Prostate. 2022 Jan;82(1):97-106. doi: 10.1002/pros.24251. Epub 2021 Oct 11. PubMed |
| CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy. Jiang L, Liang J, Huang W, Ma J, Park KH, Wu Z, Chen P, Zhu H, Ma JJ, Cai W, Paul C, Niu L, Fan GC, Wang HS, Kanisicak O, Xu M, Wang Y. Mol Ther. 2022 Jan 5;30(1):54-74. doi: 10.1016/j.ymthe.2021.10.015. Epub 2021 Oct 20. PubMed |
| Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer. Peng WX, Koirala P, Zhou H, Jiang J, Zhang Z, Yang L, Mo YY. Cell Death Dis. 2021 Oct 25;12(11):1000. doi: 10.1038/s41419-021-04288-1. PubMed |
| The Fusion of CLEC12A and MIR223HG Arises from a trans-Splicing Event in Normal and Transformed Human Cells. Dhungel BP, Monteuuis G, Giardina C, Tabar MS, Feng Y, Metierre C, Ho S, Nagarajah R, Fontaine ARM, Shah JS, Gokal D, Bailey CG, Schmitz U, Rasko JEJ. Int J Mol Sci. 2021 Nov 10;22(22). pii: ijms222212178. doi: 10.3390/ijms222212178. PubMed |
| Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists. Grinkevitch V, Wappett M, Crawford N, Price S, Lees A, McCann C, McAllister K, Prehn J, Young J, Bateson J, Gallagher L, Michaut M, Iyer V, Chatzipli A, Barthorpe S, Ciznadija D, Sloma I, Wesa A, Tice DA, Wessels L, Garnett M, Longley DB, McDermott U, McDade SS. Mol Cancer Ther. 2022 Apr 1;21(4):594-606. doi: 10.1158/1535-7163.MCT-21-0532. PubMed |
| Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties. Hirakawa MP, Tjahjono N, Light YK, Celebi AN, Celebi NN, Chintalapudi P, Butler KS, Branda SS, Krishnakumar R. iScience. 2022 Jan 12;25(2):103759. doi: 10.1016/j.isci.2022.103759. eCollection 2022 Feb 18. PubMed |
| A genome-wide CRISPR activation screen reveals Hexokinase 1 as a critical factor in promoting resistance to multi-kinase inhibitors in hepatocellular carcinoma cells. Sofer S, Lamkiewicz K, Armoza Eilat S, Partouche S, Marz M, Moskovits N, Stemmer SM, Shlomai A, Sklan EH. FASEB J. 2022 Mar;36(3):e22191. doi: 10.1096/fj.202101507RR. PubMed |
| CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Joung J, Kirchgatterer PC, Singh A, Cho JH, Nety SP, Larson RC, Macrae RK, Deasy R, Tseng YY, Maus MV, Zhang F. Nat Commun. 2022 Mar 25;13(1):1606. doi: 10.1038/s41467-022-29205-8. PubMed |
| Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons. Giehrl-Schwab J, Giesert F, Rauser B, Lao CL, Hembach S, Lefort S, Ibarra IL, Koupourtidou C, Luecken MD, Truong DJ, Fischer-Sternjak J, Masserdotti G, Prakash N, Ninkovic J, Holter SM, Vogt Weisenhorn DM, Theis FJ, Gotz M, Wurst W. EMBO Mol Med. 2022 May 9;14(5):e14797. doi: 10.15252/emmm.202114797. Epub 2022 Apr 4. PubMed |
| Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery. Zhou T, Zhu X, Ye Z, Wang YF, Yao C, Xu N, Zhou M, Ma J, Qin Y, Shen Y, Tang Y, Yin Z, Xu H, Zhang Y, Zang X, Ding H, Yang W, Guo Y, Harley JB, Namjou B, Kaufman KM, Kottyan LC, Weirauch MT, Hou G, Shen N. Nat Commun. 2022 Apr 6;13(1):1855. doi: 10.1038/s41467-022-29514-y. PubMed |
| Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production. Feser CJ, Lees CJ, Lammers DT, Riddle MJ, Bingham JR, Eckert MJ, Tolar J, Osborn MJ. Int J Mol Sci. 2022 May 3;23(9). pii: ijms23095090. doi: 10.3390/ijms23095090. PubMed |
| Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction. Huang M, Yang F, Zhang D, Lin M, Duan H, El-Mayta R, Zhang L, Qin L, Shewale SV, Pei L, Mitchell MJ, Rader DJ, Fan Y, Gong Y. Nat Cardiovasc Res. 2022 Apr;1(4):372-388. doi: 10.1038/s44161-022-00047-3. Epub 2022 Apr 13. PubMed |
| Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration. Zhang Q, Wang S, Li W, Yau E, Hui H, Singh PK, Achuthan V, Young Karris MA, Engelman AN, Rana TM. Nucleic Acids Res. 2022 Jun 17. pii: 6609817. doi: 10.1093/nar/gkac464. PubMed |
| ARID1A loss derepresses a group of human endogenous retrovirus-H loci to modulate BRD4-dependent transcription. Yu C, Lei X, Chen F, Mao S, Lv L, Liu H, Hu X, Wang R, Shen L, Zhang N, Meng Y, Shen Y, Chen J, Li P, Huang S, Lin C, Zhang Z, Yuan K. Nat Commun. 2022 Jun 17;13(1):3501. doi: 10.1038/s41467-022-31197-4. PubMed |
| A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells. Fu H, Wang T, Kong X, Yan K, Yang Y, Cao J, Yuan Y, Wang N, Kee K, Lu ZJ, Xi Q. Nat Commun. 2022 Jul 9;13(1):3984. doi: 10.1038/s41467-022-31762-x. PubMed |
| Constitutive heterochromatin propagation contributes to the X chromosome inactivation. Shevchenko AI, Rifel NA, Zakian SM, Zakharova IS. Chromosome Res. 2022 Dec;30(4):289-307. doi: 10.1007/s10577-022-09706-4. Epub 2022 Aug 3. PubMed |
| A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility. Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW, Brennand KJ, Fullard JF, Roussos P. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. PubMed |
| Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival. Khatib JB, Schleicher EM, Jackson LM, Dhoonmoon A, Moldovan GL, Nicolae CM. Oncotarget. 2022 Sep 28;13:1078-1091. doi: 10.18632/oncotarget.28277. eCollection 2022. PubMed |
The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A.
Beucher A, Miguel-Escalada I, Balboa D, De Vas MG, Maestro MA, Garcia-Hurtado J, Bernal A, Gonzalez-Franco R, Vargiu P, Heyn H, Ravassard P, Ortega S, Ferrer J.
Nat Cell Biol. 2022 Oct 6. pii: 10.1038/s41556-022-00996-8. doi: 10.1038/s41556-022-00996-8.
PubMed
Associated Plasmids |
| Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus. Hou G, Zhou T, Xu N, Yin Z, Zhu X, Zhang Y, Cui Y, Ma J, Tang Y, Cheng Z, Shen Y, Chen Y, Zou LH, Wang YF, Yin Z, Guo Y, Ding H, Ye Z, Shen N. Arthritis Rheumatol. 2023 Apr;75(4):574-585. doi: 10.1002/art.42390. Epub 2023 Feb 8. PubMed |
| KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA-DNA triplexes and HP1 binding. Zhang X, Jiang Q, Li J, Zhang S, Cao Y, Xia X, Cai D, Tan J, Chen J, Han JJ. Nat Cell Biol. 2022 Nov;24(11):1617-1629. doi: 10.1038/s41556-022-01008-5. Epub 2022 Oct 20. PubMed |
| The AhR-SRC axis as a therapeutic vulnerability in BRAFi-resistant melanoma. Paris A, Tardif N, Baietti FM, Berra C, Leclair HM, Leucci E, Galibert MD, Corre S. EMBO Mol Med. 2022 Dec 7;14(12):e15677. doi: 10.15252/emmm.202215677. Epub 2022 Oct 28. PubMed |
| MACC1 promotes pancreatic cancer metastasis by interacting with the EMT regulator SNAI1. Zhang X, Luo Y, Cen Y, Qiu X, Li J, Jie M, Yang S, Qin S. Cell Death Dis. 2022 Nov 4;13(11):923. doi: 10.1038/s41419-022-05285-8. PubMed |
| Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8. Wang N, He J, Feng X, Liao S, Zhao Y, Tang F, Kee K. Elife. 2023 Jan 5;12:e78421. doi: 10.7554/eLife.78421. PubMed |
| Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation. Jin Q, Liu X, Zhuang Z, Huang J, Gou S, Shi H, Zhao Y, Ouyang Z, Liu Z, Li L, Mao J, Ge W, Chen F, Yu M, Guan Y, Ye Y, Tang C, Huang R, Wang K, Lai L. Genome Biol. 2023 Jan 17;24(1):8. doi: 10.1186/s13059-023-02851-x. PubMed |
| Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection. King CR, Liu Y, Amato KA, Schaack GA, Hu T, Smith JA, Mehle A. bioRxiv. 2023 Feb 7:2023.02.07.527556. doi: 10.1101/2023.02.07.527556. Preprint. PubMed |
| CRISPR-Based KCC2 Upregulation Attenuates Drug-Resistant Seizure in Mouse Models of Epilepsy. Shi J, Xin H, Shao Y, Dai S, Tan N, Li Z, Fei F, Wu D, Wang Y, Ping Y, Chen Z. Ann Neurol. 2023 Jul;94(1):91-105. doi: 10.1002/ana.26656. Epub 2023 Apr 22. PubMed |
| Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus. Gil N, Perry RB, Mukamel Z, Tuck A, Buhler M, Ulitsky I. Cell Rep. 2023 May 30;42(6):112569. doi: 10.1016/j.celrep.2023.112569. PubMed |
| Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer. Couto JP, Vulin M, Jehanno C, Coissieux MM, Hamelin B, Schmidt A, Ivanek R, Sethi A, Brautigam K, Frei AL, Hager C, Manivannan M, Gomez-Miragaya J, Obradovic MM, Varga Z, Koelzer VH, Mertz KD, Bentires-Alj M. EMBO J. 2023 Jul 3;42(13):e112559. doi: 10.15252/embj.2022112559. Epub 2023 Jun 1. PubMed |
| Integrative CRISPR Activation and Small Molecule Inhibitor Screening for lncRNA Mediating BRAF Inhibitor Resistance in Melanoma. Shamloo S, Kloetgen A, Petroulia S, Hockemeyer K, Sievers S, Tsirigos A, Aifantis I, Imig J. Biomedicines. 2023 Jul 21;11(7):2054. doi: 10.3390/biomedicines11072054. PubMed |
| Targeted CRISPR activation and knockout screenings identify novel doxorubicin transporters. Li Y, Tan M, Sun S, Stea E, Pang B. Cell Oncol (Dordr). 2023 Jul 31. doi: 10.1007/s13402-023-00847-0. PubMed |
| GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Ravid Lustig L, Sampath Kumar A, Schwammle T, Dunkel I, Noviello G, Limberg E, Weigert R, Pacini G, Buschow R, Ghauri A, Stotzel M, Wittler L, Meissner A, Schulz EG. Nat Cell Biol. 2023 Nov;25(11):1704-1715. doi: 10.1038/s41556-023-01266-x. Epub 2023 Nov 6. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.