167,564 results
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  Plasmid#141137Purposecontrolling the actin-severing ability of cofilin with lightDepositorInsertZdk2, Cofilin, LOV2
 ExpressionMammalianMutationmCherry, Zdk2(132F), Cofilin S3A, LOV WTAvailable SinceDec. 10, 2020AvailabilityAcademic Institutions and Nonprofits only
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  pEFIRES-P-ACSL3-mCherryPlasmid#87158PurposeFluorescent protein targeted to lipid droplets (LDs) from the endoplasmic reticulum (ER)DepositorAvailable SinceMay 30, 2017AvailabilityAcademic Institutions and Nonprofits only
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  PH-Akt-GFPPlasmid#51465PurposeIs a biosensor for PIP3/PI(3,4)P2DepositorInsertAKT (aa 1–164)
 TagsEGFPExpressionMammalianPromoterCMVAvailable SinceMarch 26, 2014AvailabilityAcademic Institutions and Nonprofits only
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  pAAV_hSyn1-SIO-stGtACR2-FusionRed (AAV Retrograde)Viral Prep#105677-AAVrgPurposeReady-to-use AAV Retrograde particles produced from pAAV_hSyn1-SIO-stGtACR2-FusionRed (#105677). In addition to the viral particles, you will also receive purified pAAV_hSyn1-SIO-stGtACR2-FusionRed plasmid DNA. Synapsin-driven, Cre-dependent, soma-targeted anion-conducting channelrhodopsin fused to FusionRed for optogenetic inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynTagsFusionRed (Cre-dependent)Available SinceJuly 8, 2020AvailabilityAcademic Institutions and Nonprofits only
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  AiP11390-pAAV-DLX2.0-minBG-SYFP2-WPRE3-BGHpA (Alias: CN1390)Plasmid#163505PurposeDLX2.0 (3xCore version of DLX enhancer). AAV vector for strong & rapid SYFP2 expression in forebrain GABAergic interneurons. The enhancer core has 100% seq conservation between mouse and humanDepositorHas ServiceAAV PHP.eBInsertSYFP2
 UseAAVPromoterminBetaGlobinAvailable SinceFeb. 25, 2021AvailabilityAcademic Institutions and Nonprofits only
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  Proinsulin-NanoLuc in pLX304Plasmid#62057PurposeLuminescent reporter of insulin secretionDepositorInsertProinsulin-NanoLuc (Ins2 Synthetic, Mouse)
 UseLentiviral and LuciferaseExpressionMammalianMutationInserted NanoLuc into C-peptide of mouse Ins2 cod…PromoterCMVAvailable SinceJan. 20, 2015AvailabilityAcademic Institutions and Nonprofits only
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  pLKO.1 neoPlasmid#13425Purpose3rd gen lentiviral backbone for cloning and expression of new shRNA sequences. Uses neomycin for selection.DepositorInsertnon-hairpin 18bp
 UseLentiviral and RNAiExpressionMammalianPromoterU6 promoterAvailable SinceDec. 22, 2006AvailabilityAcademic Institutions and Nonprofits only
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  pHN922Plasmid#178975PurposeExpression of GST-His8-GFP-nanobodyDepositorInsertGST-His8-GFP-nanobody
 UseAffinity Reagent/ AntibodyTagsGST, His8ExpressionBacterialPromotertacAvailable SinceFeb. 22, 2022AvailabilityAcademic Institutions and Nonprofits only
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  pAAV-CaMKIIa-mCherry (AAV9)Viral Prep#114469-AAV9PurposeReady-to-use AAV9 particles produced from pAAV-CaMKIIa-mCherry (#114469). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-mCherry plasmid DNA. CamKIIa-driven expression of mCherry. These AAV preparations are suitable purity for injection into animals.DepositorPromoterCaMKIITagsmCherryAvailable SinceJan. 6, 2022AvailabilityAcademic Institutions and Nonprofits only
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  PX459v3Plasmid#178799PurposeSpCas9 with 2A-Puro, and a golden gate cloning backbone for sgRNA. sgRNA scaffold seqeuence has been modified for increased sgRNA expression (v3).DepositorTypeEmpty backboneUseCRISPRExpressionMammalianPromoterCbh (Cas9-2A Puro) and U6 (gRNA)Available SinceAug. 9, 2024AvailabilityAcademic Institutions and Nonprofits only
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  TRPML1-G-GECO1.2-ERESPlasmid#207144PurposeFusion of Ca2+ reporter and lysosomal Ca2+-permeable channel, with ER-export signalDepositorInsertMcoln1 (MCOLN1 Human)
 TagsER-Export Signal (ERES) and G-GECO1.2ExpressionMammalianPromoterCMVAvailable SinceNov. 6, 2023AvailabilityAcademic Institutions and Nonprofits only
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  pSLQ9834_sgBB: pHR-hU6-CasMINI sgRNA_#2; EF1a-Puro-T2A-BFP- WPREPlasmid#180280PurposeThe CasMINI sgRNA cloning backbone with sites 'BsmBI' for inserting new guide sequences.DepositorInsertCasMINI sgRNA (backbone) and BFP
 UseLentiviralExpressionMammalianPromoterU6Available SinceMarch 14, 2022AvailabilityAcademic Institutions and Nonprofits only
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  pAAV.Syn.NES-jRGECO1a.WPRE.SV40 (AAV PHP.eB)Viral Prep#100854-PHPeBPurposeReady-to-use AAV PHP.eB particles produced from pAAV.Syn.NES-jRGECO1a.WPRE.SV40 (#100854). In addition to the viral particles, you will also receive purified pAAV.Syn.NES-jRGECO1a.WPRE.SV40 plasmid DNA. Synapsin-driven GECO1a calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynAvailable SinceJuly 24, 2020AvailabilityAcademic Institutions and Nonprofits only
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  pENN.AAV.hSyn.Cre.WPRE.hGH (AAV8)Viral Prep#105553-AAV8PurposeReady-to-use AAV8 particles produced from pENN.AAV.hSyn.Cre.WPRE.hGH (#105553). In addition to the viral particles, you will also receive purified pENN.AAV.hSyn.Cre.WPRE.hGH plasmid DNA. hSyn-driven Cre expression. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynAvailable SinceMarch 12, 2021AvailabilityAcademic Institutions and Nonprofits only
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  SeeSaw Reporter (SSR2.0)Plasmid#50393PurposeSSR2.0 has two target sites in opposite orientation for generate only one cycle of repairing after I-SceI endonuclease expression.DepositorInsertSSR2.0
 ExpressionMammalianPromoterCMVAvailable SinceFeb. 14, 2014AvailabilityAcademic Institutions and Nonprofits only
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  pPB_TRE3G_scFV-sfGFP-Setd2CDPlasmid#235579PurposeDox-inducible expression of the catalytic-domain (CD) of epigenetic effector Setd2 fused with scFV to programme H3K36me3DepositorInsertSetd2 (Setd2 Mouse)
 UseCRISPRAvailable SinceApril 29, 2025AvailabilityAcademic Institutions and Nonprofits only
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  pEF6-myc-TBC1D15Plasmid#79148Purposemammalian expression of TBC1D15DepositorInsertTBC1D15 (Tbc1d15 Mouse)
 TagsHis, Myc, and V5ExpressionMammalianMutationS616N (please see depositor comment below)PromoterEF-1alphaAvailable SinceAug. 9, 2016AvailabilityAcademic Institutions and Nonprofits only
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  pcDNA3/UBC9Plasmid#20082DepositorInsertUBC9 (UBE2I Human)
 ExpressionMammalianAvailable SinceJan. 9, 2009AvailabilityAcademic Institutions and Nonprofits only
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  pEGFPC1-EPSIN 1Plasmid#22228DepositorInsertEpsin 1 (Epn1 Rat)
 TagsGFPExpressionBacterial and MammalianMutationplease see depositor comment belowAvailable SinceOct. 9, 2009AvailabilityAcademic Institutions and Nonprofits only
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  AAV-CamKIIa-jGCaMP8f-WPRE (AAV5)Viral Prep#176750-AAV5PurposeReady-to-use AAV5 particles produced from AAV-CamKIIa-jGCaMP8f-WPRE (#176750). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8f-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.DepositorPromoterCamKIIalphaAvailable SinceMarch 20, 2024AvailabilityAcademic Institutions and Nonprofits only
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  pUC19 - T7 pro - IRES - EGFPPlasmid#138586PurposeExpress EGFP with an upstream T7 promoter in pUC19 backboneDepositorInsertEGFP
 Available SinceMarch 24, 2020AvailabilityAcademic Institutions and Nonprofits only
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  pAAV-hsyn-GRAB_rDA1m (AAV9)Viral Prep#140556-AAV9PurposeReady-to-use AAV9 particles produced from pAAV-hsyn-GRAB_rDA1m (#140556). In addition to the viral particles, you will also receive purified pAAV-hsyn-GRAB_rDA1m plasmid DNA. Synapsin-driven expression of red fluorescent medium affinity dopamine sensor GRAB_rDA1m. These AAV preparations are suitable purity for injection into animals.DepositorPromoterSynAvailable SinceAug. 31, 2021AvailabilityAcademic Institutions and Nonprofits only
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  pAAV-S5E2-GFP-fGFPPlasmid#135631PurposeAAV vector to drive the expression of fGFP in PV cortical interneuronsunder the control of the E2 regulatory elementDepositorHas ServiceAAV PHP.eB, AAV1, and AAV9InsertGFP-fGFP
 UseAAVMutationNoneAvailable SinceAug. 17, 2020AvailabilityAcademic Institutions and Nonprofits only
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  pEF1a-FB-dCas9-puroPlasmid#100547PurposeExpresses N-terminal Flag and biotin-acceptor-site (FB)-tagged dCas9 proteinDepositorInsertsN-terminal Flag and biotin-acceptor-site (FB)-tagged dCas9
 puromycin
 UseCRISPRTagsFLAG, Biotin-acceptor-site (Avitag)ExpressionMammalianPromoterHuman EF1aAvailable SinceSept. 7, 2017AvailabilityAcademic Institutions and Nonprofits only
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  Ultra-Exon1Q23-Myc-APlasmid#110486PurposeLentiviral vector to express wild-type N terminal HTT gene with short 3'UTR in mammalian cells (encodes Myc-tagged wild type huntingtin exon1 fragment with 23 repeats of Q)DepositorInsertHomo sapiens huntingtin (HTT Human)
 UseLentiviralTagsMycExpressionMammalianMutationShort 3'UTR wild type huntingtin exon1 fragm…PromoterUbCAvailable SinceJuly 18, 2019AvailabilityAcademic Institutions and Nonprofits only
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  pAAV-FLEX-tdTomato (AAV8)Viral Prep#28306-AAV8PurposeReady-to-use AAV8 particles produced from pAAV-FLEX-tdTomato (#28306). In addition to the viral particles, you will also receive purified pAAV-FLEX-tdTomato plasmid DNA. CAG-driven, Cre-dependent tdTomato expression control. These AAV preparations are suitable purity for injection into animals.DepositorPromoterCAGTagstdTomato (Cre-dependent)Available SinceOct. 18, 2021AvailabilityAcademic Institutions and Nonprofits only
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  pGP-AAV-syn-jGCaMP8s-WPREPlasmid#162374PurposeAAV-mediated expression of ultrafast protein calcium sensor under the Syn promoterDepositorHas ServiceAAV Retrograde, AAV1, AAV5, and AAV9InsertjGCaMP8s
 UseAAVTags6xHisExpressionMammalianMutationS26M F286Y Q315HPromoterSynapsinAvailable SinceNov. 30, 2020AvailabilityAcademic Institutions and Nonprofits only
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  pCMV_AncBE4max_P2A_GFPPlasmid#112100PurposeC:G-to-T:A base editingDepositorInsertAncBE4max_P2A_GFP
 UseCRISPRExpressionMammalianPromoterCMVAvailable SinceJune 7, 2018AvailabilityAcademic Institutions and Nonprofits only
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  pWALIUM10-V5-TurboID-GWPlasmid#196285PurposeGateway destination vector to express N-terminal TurboID fusion under UAS promoter, for making transgenic fliesDepositorTypeEmpty backboneUseGateway destination vectorExpressionInsectAvailable SinceMarch 21, 2024AvailabilityAcademic Institutions and Nonprofits only
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  pCDNA6A-EGFR WTPlasmid#42665DepositorAvailable SinceJune 17, 2013AvailabilityAcademic Institutions and Nonprofits only
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  pCMV6-Neo-ISG15-LRAAPlasmid#80405Purposeoverexpression of nonconjugative ISG15DepositorAvailable SinceDec. 15, 2020AvailabilityAcademic Institutions and Nonprofits only
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  pCI-VSVGPlasmid#1733PurposeVSV-G expressing envelope vector; recommended for the FELIX (FIV-based) vector system from the Nolan labDepositorInsertVSV-G Envelope
 ExpressionMammalianAvailable SinceJune 20, 2005AvailabilityAcademic Institutions and Nonprofits only
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  pINDUCER13 miR-200c-141Plasmid#81020PurposeLentiviral vector containing doxycycline inducible human miR-200c. Puromycin selectable.DepositorInsertmiR-200c (MIR200C Human)
 UseLentiviralAvailable SinceAug. 10, 2016AvailabilityAcademic Institutions and Nonprofits only
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  GFP-RelAPlasmid#23255DepositorAvailable SinceMarch 10, 2010AvailabilityAcademic Institutions and Nonprofits only
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  pFUW-TetO-NFATC2Plasmid#207191Purposedoxycycline-inducible expression of Human NFATC2 in mammalian cellsDepositorInsertpFUW-TetO-NFATC2
 UseLentiviralExpressionMammalianPromoterCMVAvailable SinceAug. 29, 2025AvailabilityAcademic Institutions and Nonprofits only
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  pAAV-CAG-GFP (AAV6)Viral Prep#37825-AAV6PurposeReady-to-use AAV6 particles produced from pAAV-CAG-GFP (#37825). In addition to the viral particles, you will also receive purified pAAV-CAG-GFP plasmid DNA. CAG-driven GFP expression. These AAV preparations are suitable purity for injection into animals.DepositorPromoterCAGTagsGFPAvailable SinceJuly 16, 2025AvailabilityAcademic Institutions and Nonprofits only
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  pBbS5a-OptoCre-REDMAPPlasmid#228465PurposeLight-inducible Cre recombinase split with REDMAP photoreceptors for bacterial expressionDepositorInsertOptoCre-REDMAP
 UseCre/LoxExpressionBacterialPromoterpLacUV5Available SinceMarch 12, 2025AvailabilityAcademic Institutions and Nonprofits only
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  pUC57-LbNOXPlasmid#75285PurposeThis plasmid contains human codon optimized sequence of LbNOX which is a water-forming NADH oxidase that can be used to increase NAD+/NADH ratio in mammalian cells.DepositorInsertLbNOX
 TagsC-terminal FLAG tag with linkerMutationHuman codon optimizedAvailable SinceMay 17, 2016AvailabilityAcademic Institutions and Nonprofits only
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  mEmerald-Desmin-C-18Plasmid#54059PurposeLocalization: Intermediate Filaments, Excitation: 487, Emission: 509DepositorAvailable SinceJuly 2, 2014AvailabilityIndustry, Academic Institutions, and Nonprofits
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  CMV-CASANOVAPlasmid#113035PurposeCASANOVA (AcrIIA4-LOV2 hybrid) expression in mammalian cells; enables optogenetic control of SpyCas9DepositorInsertCASANOVA (for CRISPR/Cas9 activity switching via a novel optogenetic variant of AcrIIA4)
 UseCRISPR and Synthetic BiologyExpressionMammalianAvailable SinceOct. 31, 2018AvailabilityAcademic Institutions and Nonprofits only
 
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
       
      