171,694 results
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Plasmid#121456Purposeexpression of human PD-L1 mutant in mammalian cellsDepositorAvailable SinceFeb. 2, 2021AvailabilityAcademic Institutions and Nonprofits only
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TET-pLKO.1 PURO shSMAD4 #2
Plasmid#83091PurposeLentiviral shRNA vector for inducible knockdown of human SMAD4DepositorAvailable SinceFeb. 28, 2019AvailabilityAcademic Institutions and Nonprofits only -
pD649-HAsp-CD5-Fc(DAPA)-AviTag-6xHis
Plasmid#156793PurposeMammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.DepositorInsertCD5 (CD5 Human)
TagsFc(DAPA)-AviTag-6xHisExpressionMammalianMutationFc region of human IgG contains D265A and P329A m…PromoterCMV/SP6Available SinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDF0039 DisCas7-11 only expression with CRISPR array
Plasmid#172500PurposeEncodes the DisCas7-11 protein only for bacterial expressionDepositorInsertDisCas7-11 only expression with CRISPR array
ExpressionBacterialAvailable SinceNov. 5, 2021AvailabilityAcademic Institutions and Nonprofits only -
pSW002-PpsbA
Plasmid#108236PurposeBroad host bacterial expression vector with constitutive PsbA promoterDepositorInsertPsbA promoter
ExpressionBacterialAvailable SinceMay 7, 2018AvailabilityAcademic Institutions and Nonprofits only -
pBSVSG221KOblast
Plasmid#59733PurposeFor replacement of VSG221 with a blasticidin resistence gene in the VSG221 expression site in T.brucei.DepositorInsertVSG221 knockout construct
UseFor homologous recombination into vsg221 expressi…Available SinceJuly 15, 2015AvailabilityAcademic Institutions and Nonprofits only -
pR6K-GFP-RFP
Plasmid#199652PurposeR6K backbone with Golden Gate (GG) cloning sitesDepositorTypeEmpty backboneExpressionBacterialPromoterJ23119 promoterAvailable SinceMay 3, 2024AvailabilityAcademic Institutions and Nonprofits only -
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pCAG-mEGFP-CaMKIIa (T305D/T306D)
Plasmid#127611PurposeFluorescent reporter for mutant Ca2+/calmodulin-dependent protein kinase II alpha (T305D/T306D)DepositorInsertcalcium/calmodulin-dependent protein kinase II alpha (Camk2a Rat)
TagsmEGFPExpressionMammalianMutationchanged Threonine 305/306 to AlaninePromoterpCAGAvailable SinceJan. 25, 2020AvailabilityAcademic Institutions and Nonprofits only -
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pAPM-D4 miR30-HDAC1 ts1
Plasmid#115852PurposeHDAC1 knockdownDepositorAvailable SinceApril 1, 2019AvailabilityAcademic Institutions and Nonprofits only -
pGEX-4T-3-TRC8 513-664
Plasmid#185352PurposeRING domain-containing GST fusion protein for ubiquitination assays.DepositorAvailable SinceAug. 1, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCDH-puro/Flag PD-L1 N200Q/N219Q
Plasmid#121454Purposeexpression of human PD-L1 mutant in mammalian cellsDepositorInsertCD274 (CD274 Human)
UseLentiviralTagsFlagExpressionMammalianMutationN200Q/N219QPromoterCMVAvailable SinceFeb. 2, 2021AvailabilityAcademic Institutions and Nonprofits only -
pDONR221-SLC44A1_STOP
Plasmid#161079PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.DepositorInsertSLC44A1 (SLC44A1 Human)
ExpressionMammalianAvailable SinceJune 21, 2021AvailabilityIndustry, Academic Institutions, and Nonprofits -
p221- purVSG117UTR
Plasmid#59732PurposeInserts a puromycin resistance gene and a VSG117 gene into the VSG221 expression site of T.brucei downstream of the expression site promoter.DepositorInsertVSG117 flanked upstream and downstream by sequences homologous to the VSG221 expression site
UseFor homologous recombination into vsg221 expressi…Available SinceAug. 6, 2015AvailabilityAcademic Institutions and Nonprofits only -
pDONR221-olig1
Plasmid#192744PurposeGateway entry vector encoding zebrafish olig1DepositorAvailable SinceNov. 21, 2022AvailabilityAcademic Institutions and Nonprofits only -
pMKO shRNA Bmf
Plasmid#17236DepositorAvailable SinceJan. 18, 2008AvailabilityAcademic Institutions and Nonprofits only -
pCDH-puro/Flag PD-L1 N35Q
Plasmid#121449Purposeexpression of human PD-L1 mutant in mammalian cellsDepositorAvailable SinceFeb. 2, 2021AvailabilityAcademic Institutions and Nonprofits only -
pDSM-bc-Ptdh3-CAD-Ttdh1
Plasmid#127727PurposeYeast pathway position 3. CAD transcription unit with the TDH3 promoter and TDH1 terminator.DepositorInsertcis-aconitate decarboxylase
UseSynthetic BiologyExpressionYeastPromoterPtdh3Available SinceMarch 1, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDONR221-SLC25A16_STOP
Plasmid#161145PurposeGateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.DepositorInsertSLC25A16 (SLC25A16 Human)
ExpressionMammalianAvailable SinceJune 21, 2021AvailabilityIndustry, Academic Institutions, and Nonprofits -
pAPM-D4 miR30-HDAC1 ts3
Plasmid#115849PurposeHDAC1 knockdownDepositorAvailable SinceSept. 5, 2019AvailabilityAcademic Institutions and Nonprofits only -
pAPM-D4 miR30-HDAC1 ts2
Plasmid#115848PurposeHDAC1 knockdownDepositorAvailable SinceSept. 5, 2019AvailabilityAcademic Institutions and Nonprofits only -
pFB-U6-Chrna3-gRNA-hSyn-mCherry-WPRE-SV40pA
Plasmid#128338PurposepAAV encoding gRNA sequence for loss-of-function indelsDepositorAvailable SinceJuly 19, 2019AvailabilityAcademic Institutions and Nonprofits only -
pAc.1B-EGFP-DmHrb98
Plasmid#66595PurposeExpresses EGFP-tagged Hrb98 in Drosophila cellsDepositorAvailable SinceJune 24, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLX304-G3BP1-Lantern
Plasmid#250918PurposeExpresses Lantern fused to G3BP1 in mammalian cells for targeting to stress granulesDepositorInsertLantern
UseLentiviralTagsV5-G3BP1ExpressionMammalianPromoterCMVAvailable SinceJan. 28, 2026AvailabilityAcademic Institutions and Nonprofits only -
pLX304-Lantern-HaloTag-NES
Plasmid#250919PurposeExpresses Lantern in mammalian cytosolDepositorInsertLantern
UseLentiviralTagsHaloTag-NES and V5ExpressionMammalianPromoterCMVAvailable SinceJan. 28, 2026AvailabilityAcademic Institutions and Nonprofits only -
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pXeDNA3.1-LacZ
Plasmid#242746PurposepXeDNA3-LacZ TA-cloning vector for dual expression: CMV enhancer/promoter in mammalian cells and Xenopus β-globin 5'/3'UTRs in oocytes; BGHpA, AmpR, NeoR, lacZα for blue-white screening.DepositorTypeEmpty backboneUseXenopus oocyte expressionExpressionMammalianPromoterCMVAvailable SinceNov. 4, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn1-DIO-SEP-GluA2Q
Plasmid#227234PurposeLarge cargo capacity AAV that expresses SEP tagged AMPA receptor subunit GluA2 R607Q mutant in neurons expressing Cre recombinaseDepositorInsertSEP-GluA2 (Gria2 )
UseAAVTagssuperecliptic pHluorinExpressionMammalianMutationQ607RPromoterhSyn1Available SinceOct. 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
p131C-B10
Plasmid#241908PurposeOptimised PCA biosensor produced sfGFP in response to hydroxyl-substituted benzoic acids, including protocatechuic acid (PCA)DepositorInsertpcaV, sfGFP
UseSynthetic BiologyMutationnoneAvailable SinceAug. 27, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP14703 - pAAV-AiE2135m-minBG-iCre(R297T)-BGHpA (Alias: CN4703)
Plasmid#229925PurposeAiE2135m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific brain cell typesDepositorInsertiCre(R297T)
UseAAVAvailable SinceAug. 19, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV_hSyn1_HyPer7_mito
Plasmid#238968PurposeMammalian neurons HyPer7 expression targeted to the mitochondrial matrixDepositorInsertHyPer7
UseAAVTags3x Cytochrome C Oxidase Subunit VIII presequenseExpressionMammalianPromoterhSyn1Available SinceAug. 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV_Ckm_F9
Plasmid#226140PurposeAAV construct for HITI insert with Ckm gRNA and hF9 transgeneDepositorAvailable SinceAug. 4, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
pL6puro-JeT-pmRevErbA-mClover3-NLS-Pest
Plasmid#240109PurposeA lentiviral (yellow-green) fluorescent reporter of circadian rhythm, based on the murine Nr1d1-gene (REVERBa protein), expression enhanced by synthtic JeT promoter.DepositorInsertmurine Nr1d1 promoter+mClover3-NLS-Pest-Reporter (Nr1d1 Mouse)
UseLentiviralMutationadded JeT PromoterAvailable SinceAug. 4, 2025AvailabilityAcademic Institutions and Nonprofits only -
LgBiT-NCK1 Fusion Vector
Plasmid#237025PurposeExpress LgBiT-NCK1 Fusion Protein in Mammalian Cells under a CMV promoterDepositorAvailable SinceJuly 14, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits -
SpRY-Tad-CBE(CCG3)
Plasmid#235083PurposeExpresses SpRY-Tad-CBE(CCG3) in mammalian cells.DepositorInsertTad-CBE(CCG3)-SpRY Cas9 D10A
UseCRISPRTags2xUGI, bpNLS and bpNLSExpressionMammalianAvailable SinceJuly 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
Tad-CBE(GCA1)
Plasmid#235075PurposeExpresses Tad-CBE(GCA1) in mammalian cells.DepositorInsertTad-CBE(GCA1)-SpCas9 D10A
UseCRISPRTags2xUGI, bpNLS and bpNLSExpressionMammalianAvailable SinceJuly 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
TFORF0705
Plasmid#143727PurposeLentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.DepositorAvailable SinceMay 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
PDG458 eSp(1.1) V3
Plasmid#226964PurposeCBh-eSpCas9(1.1)-2A-GFP, and 2X hU6-sgRNA (Sp) with BbsI golden gate cloning backbone dual gRNAs. sgRNA uses 3TC scaffold for increased sgRNA expression.DepositorTypeEmpty backboneUseCRISPRExpressionMammalianAvailable SinceOct. 30, 2024AvailabilityAcademic Institutions and Nonprofits only -
PX459v3-eSpCas9(1.1)
Plasmid#178800PurposeHigh-fidelity eSpCas9(1.1) with 2A-Puro, and a golden gate cloning backbone for sgRNA. sgRNA scaffold seqeuence has been modified for increased sgRNA expression (v3).DepositorTypeEmpty backboneUseCRISPRExpressionMammalianPromoterCbh (Cas9-2A Puro) and U6 (gRNA)Available SinceAug. 9, 2024AvailabilityAcademic Institutions and Nonprofits only -
AGTR2-DuET
Plasmid#213184PurposeThe DuET construct encodes the named human GPCR engineered with a cleaved hemagglutinin signal peptide, a 5' FLAG and a 3' 1D4 epitope tag optimized for expression in mammalian cells and proteomics studies.DepositorAvailable SinceApril 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
pD649-HAsp-LILRA2-Fc(DAPA)-AviTag-6xHis
Plasmid#156856PurposeMammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.DepositorInsertLILRA2 (LILRA2 Human)
TagsFc(DAPA)-AviTag-6xHisExpressionMammalianMutationFc region of human IgG contains D265A and P329A m…PromoterCMV/SP6Available SinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pD649-HAsp-HLA-G-Fc(DAPA)-AviTag-6xHis
Plasmid#156833PurposeMammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.DepositorInsertHLA-G (HLA-G Human)
TagsFc(DAPA)-AviTag-6xHisExpressionMammalianMutationFc region of human IgG contains D265A and P329A m…PromoterCMV/SP6Available SinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
TFORF0308
Plasmid#141574PurposeLentiviral vector for overexpressing the CREM transcription factor ORF with a unique 24-bp barcode. Barcodes facilitate identification of transcription factors in pooled screens.DepositorAvailable SinceJan. 5, 2023AvailabilityAcademic Institutions and Nonprofits only -
pFB-U6-control-gRNA-hSyn-mCherry-WPRE-SV40pA
Plasmid#128347PurposepAAV encoding control gRNA for CRISPR gRNAs listed aboveDepositorInsertcontrol (negative)
UseCRISPRExpressionMammalianAvailable SinceJuly 29, 2019AvailabilityAcademic Institutions and Nonprofits only -
pHH0103_FYB-1/2
Plasmid#91459PurposeProtein expression and purification of human SH3 domain construct FYB-1/2DepositorInsertFYB-1/2 (FYB1 Human)
ExpressionBacterialAvailable SinceMarch 19, 2018AvailabilityAcademic Institutions and Nonprofits only -
pHH0103_FYB-2/2
Plasmid#91300PurposeProtein expression and purification of human SH3 domain construct FYB-2/2DepositorInsertFYB-2/2 (FYB1 Human)
ExpressionBacterialAvailable SinceMarch 19, 2018AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CaMKIIa-hM4D(Gi)-mCherry (AAV1)
Viral Prep#50477-AAV1PurposeReady-to-use AAV1 particles produced from pAAV-CaMKIIa-hM4D(Gi)-mCherry (#50477). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM4D(Gi)-mCherry plasmid DNA. CaMKIIa-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal silencing. These AAV preparations are suitable purity for injection into animals.DepositorPromoterCaMKIITagsmCherryAvailable SinceDec. 18, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLI50
Plasmid#13573DepositorTypeEmpty backboneUseS. aureus-e. coli shuttle vectorAvailable SinceJan. 25, 2007AvailabilityAcademic Institutions and Nonprofits only -
pAAV-c-fos-CytoTape-V5
Plasmid#239429PurposeCytoTape signal monomer for recording c-fos promoter transcriptional activityDepositorInsertCytoTape-V5
UseAAVTagsV5-dMBPExpressionMammalianPromoterc-fos promoterAvailable SinceOct. 29, 2025AvailabilityIndustry, Academic Institutions, and Nonprofits