psPAX2 Citations (5151)
Originally described in: Trono Lab Packaging and Envelope PlasmidsUnpublished
Articles Citing psPAX2
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New cell lines from mouse epiblast share defining features with human embryonic stem cells. Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD. Nature. 2007 Jul 12. 448(7150):196-9. PubMed |
CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. Roca H, Varsos Z, Pienta KJ. J Biol Chem. 2008 Sep 5;283(36):25057-73. doi: 10.1074/jbc.M801073200. Epub 2008 Jul 8. PubMed |
A polypyrimidine tract-binding protein-dependent pathway of mRNA stability initiates with CpG activation of primary B cells. Porter JF, Vavassori S, Covey LR. J Immunol. 2008 Sep 1;181(5):3336-45. PubMed |
Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification. Braam SR, Denning C, Matsa E, Young LE, Passier R, Mummery CL. Nat Protoc. 2008;3(9):1435-43. doi: 10.1038/nprot.2008.140. PubMed |
The scaffold protein JSAP1 regulates proliferation and differentiation of cerebellar granule cell precursors by modulating JNK signaling. Sato T, Torashima T, Sugihara K, Hirai H, Asano M, Yoshioka K. Mol Cell Neurosci. 2008 Dec;39(4):569-78. doi: 10.1016/j.mcn.2008.08.003. Epub 2008 Aug 30. PubMed |
Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. Pendino F, Nguyen E, Jonassen I, Dysvik B, Azouz A, Lanotte M, Segal-Bendirdjian E, Lillehaug JR. Blood. 2009 Apr 2;113(14):3172-81. doi: 10.1182/blood-2008-07-170035. Epub 2009 Jan 30. PubMed |
A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, Chung RT. Cell Host Microbe. 2009 Mar 19;5(3):298-307. doi: 10.1016/j.chom.2009.02.001. PubMed |
Matrix metalloproteinase 12 silencing: a therapeutic approach to treat pathological lung tissue remodeling? Garbacki N, Di Valentin E, Piette J, Cataldo D, Crahay C, Colige A. Pulm Pharmacol Ther. 2009 Aug;22(4):267-78. doi: 10.1016/j.pupt.2009.03.001. Epub 2009 Mar 25. PubMed |
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma. Schmitz R, Hansmann ML, Bohle V, Martin-Subero JI, Hartmann S, Mechtersheimer G, Klapper W, Vater I, Giefing M, Gesk S, Stanelle J, Siebert R, Kuppers R. J Exp Med. 2009 May 11;206(5):981-9. doi: 10.1084/jem.20090528. Epub 2009 Apr 20. PubMed |
Tumor microvasculature supports proliferation and expansion of glioma-propagating cells. Borovski T, Verhoeff JJ, ten Cate R, Cameron K, de Vries NA, van Tellingen O, Richel DJ, van Furth WR, Medema JP, Sprick MR. Int J Cancer. 2009 Sep 1;125(5):1222-30. doi: 10.1002/ijc.24408. PubMed |
Tubulin polymerization-promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation. Lehotzky A, Lau P, Tokesi N, Muja N, Hudson LD, Ovadi J. Glia. 2010 Jan 15;58(2):157-68. doi: 10.1002/glia.20909. PubMed |
Long term non-invasive imaging of embryonic stem cells using reporter genes. Sun N, Lee A, Wu JC. Nat Protoc. 2009;4(8):1192-201. doi: 10.1038/nprot.2009.100. Epub 2009 Jul 23. PubMed |
Multipurpose modular lentiviral vectors for RNA interference and transgene expression. Kesireddy V, van der Ven PF, Furst DO. Mol Biol Rep. 2010 Jul;37(6):2863-70. doi: 10.1007/s11033-009-9840-8. Epub 2009 Oct 2. PubMed |
Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats. Abbott SB, Stornetta RL, Socolovsky CS, West GH, Guyenet PG. J Physiol. 2009 Dec 1. 587(Pt 23):5613-31. PubMed |
Inducible APOBEC3G-Vif double stable cell line as a high-throughput screening platform to identify antiviral compounds. Nowotny B, Schneider T, Pradel G, Schirmeister T, Rethwilm A, Kirschner M. Antimicrob Agents Chemother. 2010 Jan;54(1):78-87. doi: 10.1128/AAC.00775-09. Epub 2009 Oct 19. PubMed |
Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. Klunker S, Chong MM, Mantel PY, Palomares O, Bassin C, Ziegler M, Ruckert B, Meiler F, Akdis M, Littman DR, Akdis CA. J Exp Med. 2009 Nov 23;206(12):2701-15. doi: 10.1084/jem.20090596. Epub 2009 Nov 16. PubMed |
Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies. Frank RT, Edmiston M, Kendall SE, Najbauer J, Cheung CW, Kassa T, Metz MZ, Kim SU, Glackin CA, Wu AM, Yazaki PJ, Aboody KS. PLoS One. 2009 Dec 15;4(12):e8314. doi: 10.1371/journal.pone.0008314. PubMed |
Lentiviral gene transduction in human and mouse NK cell lines. Savan R, Chan T, Young HA. Methods Mol Biol. 2010;612:209-21. doi: 10.1007/978-1-60761-362-6_14. PubMed |
HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells. Xia D, Holla VR, Wang D, Menter DG, DuBois RN. Cancer Res. 2010 Jan 15;70(2):824-31. doi: 10.1158/0008-5472.CAN-09-2105. Epub 2010 Jan 12. PubMed |
An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cells. Falkowska-Hansen B, Kollar J, Gruner BM, Schanz M, Boukamp P, Siveke J, Rethwilm A, Kirschner M. Exp Cell Res. 2010 Jul 1;316(11):1885-95. doi: 10.1016/j.yexcr.2010.02.015. Epub 2010 Feb 18. PubMed |
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal (stromal) stem cells through canonical Wnt signaling and C/EBP. Qiu W, Hu Y, Andersen TE, Jafari A, Li N, Chen W, Kassem M. J Biol Chem. 2010 May 7;285(19):14438-49. doi: 10.1074/jbc.M109.052001. Epub 2010 Mar 11. PubMed |
Lentiviral vector-mediated transgenesis in human embryonic stem cells. Du ZW, Zhang SC. Methods Mol Biol. 2010;614:127-34. doi: 10.1007/978-1-60761-533-0_8. PubMed |
Aire regulates the expression of differentiation-associated genes and self-renewal of embryonic stem cells. Gu B, Zhang J, Chen Q, Tao B, Wang W, Zhou Y, Chen L, Liu Y, Zhang M. Biochem Biophys Res Commun. 2010 Apr 2. 394(2):418-23. PubMed |
Functional analysis of the Cdk7.cyclin H.Mat1 complex in mouse embryonic stem cells and embryos. Patel SA, Simon MC. J Biol Chem. 2010 May 14;285(20):15587-98. doi: 10.1074/jbc.M109.081687. Epub 2010 Mar 15. PubMed |
Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. Bryan NB, Dorfleutner A, Kramer SJ, Yun C, Rojanasakul Y, Stehlik C. J Inflamm (Lond). 2010 May 18;7:23. doi: 10.1186/1476-9255-7-23. PubMed |
Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex. Dettmer U, Kuhn PH, Abou-Ajram C, Lichtenthaler SF, Kruger M, Kremmer E, Haass C, Haffner C. J Biol Chem. 2010 Aug 20;285(34):26174-81. doi: 10.1074/jbc.M110.132548. Epub 2010 Jun 10. PubMed |
A novel, retromer-independent role for sorting nexins 1 and 2 in RhoG-dependent membrane remodeling. Prosser DC, Tran D, Schooley A, Wendland B, Ngsee JK. Traffic. 2010 Oct;11(10):1347-62. doi: 10.1111/j.1600-0854.2010.01100.x. PubMed |
Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding. Muck C, Herndler-Brandstetter D, Micutkova L, Grubeck-Loebenstein B, Jansen-Durr P. J Gerontol A Biol Sci Med Sci. 2010 Nov;65(11):1165-80. doi: 10.1093/gerona/glq129. Epub 2010 Jul 30. PubMed |
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. Gerin I, Clerbaux LA, Haumont O, Lanthier N, Das AK, Burant CF, Leclercq IA, MacDougald OA, Bommer GT. J Biol Chem. 2010 Oct 29;285(44):33652-61. doi: 10.1074/jbc.M110.152090. Epub 2010 Aug 22. PubMed |
Stable overexpression of miRNAs in bone marrow-derived murine mast cells using lentiviral expression vectors. Mayoral RJ, Monticelli S. Methods Mol Biol. 2010;667:205-14. doi: 10.1007/978-1-60761-811-9_14. PubMed |
Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. Chuang CH, Wallace MD, Abratte C, Southard T, Schimenti JC. PLoS Genet. 2010 Sep 9;6(9):e1001110. doi: 10.1371/journal.pgen.1001110. PubMed |
Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea. Collaco A, Marathe J, Kohnke H, Kravstov D, Ameen N. Am J Physiol Cell Physiol. 2010 Dec;299(6):C1450-60. doi: 10.1152/ajpcell.00029.2010. Epub 2010 Sep 15. PubMed |
Role for PKC delta in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells. Ruvolo VR, Karanjeet KB, Schuster TF, Brown R, Deng Y, Hinchcliffe E, Ruvolo PP. J Signal Transduct. 2010 Jan 1;2010:584657. PubMed |
Effects of estrogen on the proportion of stem cells in the breast. Simoes BM, Piva M, Iriondo O, Comaills V, Lopez-Ruiz JA, Zabalza I, Mieza JA, Acinas O, Vivanco MD. Breast Cancer Res Treat. 2011 Aug;129(1):23-35. doi: 10.1007/s10549-010-1169-4. Epub 2010 Sep 22. PubMed |
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. Mohni KN, Livingston CM, Cortez D, Weller SK. J Virol. 2010 Dec;84(23):12152-64. doi: 10.1128/JVI.01643-10. Epub 2010 Sep 22. PubMed |
Dual selection mechanisms drive efficient single-gene reverse genetics for rotavirus. Trask SD, Taraporewala ZF, Boehme KW, Dermody TS, Patton JT. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18652-7. doi: 10.1073/pnas.1011948107. Epub 2010 Oct 11. PubMed |
The SR-BI partner PDZK1 facilitates hepatitis C virus entry. Eyre NS, Drummer HE, Beard MR. PLoS Pathog. 2010 Oct 7;6(10):e1001130. doi: 10.1371/journal.ppat.1001130. PubMed |
Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice. Piedrahita D, Hernandez I, Lopez-Tobon A, Fedorov D, Obara B, Manjunath BS, Boudreau RL, Davidson B, Laferla F, Gallego-Gomez JC, Kosik KS, Cardona-Gomez GP. J Neurosci. 2010 Oct 20;30(42):13966-76. doi: 10.1523/JNEUROSCI.3637-10.2010. PubMed |
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells.
Loewer S, Cabili MN, Guttman M, Loh YH, Thomas K, Park IH, Garber M, Curran M, Onder T, Agarwal S, Manos PD, Datta S, Lander ES, Schlaeger TM, Daley GQ, Rinn JL.
Nat Genet. 2010 Dec;42(12):1113-7. Epub 2010 Nov 7.
PubMed
Associated Plasmids |
The TRAF-interacting protein (TRIP) is a regulator of keratinocyte proliferation. Almeida S, Ryser S, Obarzanek-Fojt M, Hohl D, Huber M. J Invest Dermatol. 2011 Feb;131(2):349-57. doi: 10.1038/jid.2010.329. Epub 2010 Nov 11. PubMed |
Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells. Duan L, Motchoulski N, Danzer B, Davidovich I, Shariat-Madar Z, Levenson VV. J Biol Chem. 2011 Jan 28;286(4):2864-76. doi: 10.1074/jbc.M110.143271. Epub 2010 Nov 17. PubMed |
Polypyrimidine tract-binding protein is critical for the turnover and subcellular distribution of CD40 ligand mRNA in CD4+ T cells. Matus-Nicodemos R, Vavassori S, Castro-Faix M, Valentin-Acevedo A, Singh K, Marcelli V, Covey LR. J Immunol. 2011 Feb 15;186(4):2164-71. doi: 10.4049/jimmunol.1003236. Epub 2011 Jan 17. PubMed |
Akt1 deletion prevents lung tumorigenesis by mutant K-ras. Hollander MC, Maier CR, Hobbs EA, Ashmore AR, Linnoila RI, Dennis PA. Oncogene. 2011 Apr 14;30(15):1812-21. doi: 10.1038/onc.2010.556. Epub 2011 Jan 17. PubMed |
Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a). Kosar M, Bartkova J, Hubackova S, Hodny Z, Lukas J, Bartek J. Cell Cycle. 2011 Feb 1;10(3):457-68. Epub 2011 Feb 1. PubMed |
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Zhang H, Pasolli HA, Fuchs E. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2270-5. doi: 10.1073/pnas.1019603108. Epub 2011 Jan 24. PubMed |
JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Delta716) mice. Fujishita T, Aoki M, Taketo MM. Gastroenterology. 2011 May;140(5):1556-63.e6. doi: 10.1053/j.gastro.2011.02.007. Epub 2011 Feb 12. PubMed |
High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts. Adler AF, Speidel AT, Christoforou N, Kolind K, Foss M, Leong KW. Biomaterials. 2011 May;32(14):3611-9. doi: 10.1016/j.biomaterials.2011.01.040. Epub 2011 Feb 21. PubMed |
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC. Nature. 2011 Apr 14;472(7342):221-5. doi: 10.1038/nature09879. Epub 2011 Feb 23. PubMed |
The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma. Huang P, Kishida S, Cao D, Murakami-Tonami Y, Mu P, Nakaguro M, Koide N, Takeuchi I, Onishi A, Kadomatsu K. Cancer Res. 2011 Apr 15;71(8):2938-48. doi: 10.1158/0008-5472.CAN-10-3524. Epub 2011 Feb 24. PubMed |
SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production. Bell EL, Emerling BM, Ricoult SJ, Guarente L. Oncogene. 2011 Jun 30;30(26):2986-96. doi: 10.1038/onc.2011.37. Epub 2011 Feb 28. PubMed |
Somatic coding mutations in human induced pluripotent stem cells. Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. PubMed |
S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism. Kumar A, Oskouian B, Fyrst H, Zhang M, Paris F, Saba JD. Cell Death Dis. 2011 Feb 10;2:e119. doi: 10.1038/cddis.2011.3. PubMed |
Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia. McGinley L, McMahon J, Strappe P, Barry F, Murphy M, O'Toole D, O'Brien T. Stem Cell Res Ther. 2011 Mar 7;2(2):12. doi: 10.1186/scrt53. PubMed |
Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma. Guan B, Mao TL, Panuganti PK, Kuhn E, Kurman RJ, Maeda D, Chen E, Jeng YM, Wang TL, Shih IeM. Am J Surg Pathol. 2011 May;35(5):625-32. doi: 10.1097/PAS.0b013e318212782a. PubMed |
Anthrax lethal factor activates K(+) channels to induce IL-1beta secretion in macrophages. Thomas J, Epshtein Y, Chopra A, Ordog B, Ghassemi M, Christman JW, Nattel S, Cook JL, Levitan I. J Immunol. 2011 May 1;186(9):5236-43. doi: 10.4049/jimmunol.1001078. Epub 2011 Mar 18. PubMed |
Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development. Kawazu M, Saso K, Tong KI, McQuire T, Goto K, Son DO, Wakeham A, Miyagishi M, Mak TW, Okada H. PLoS One. 2011 Mar 18;6(3):e17830. doi: 10.1371/journal.pone.0017830. PubMed |
HIV infection enhances TRAIL-induced cell death in macrophage by down-regulating decoy receptor expression and generation of reactive oxygen species. Zhu DM, Shi J, Liu S, Liu Y, Zheng D. PLoS One. 2011 Apr 5;6(4):e18291. doi: 10.1371/journal.pone.0018291. PubMed |
The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. Taxman DJ, Holley-Guthrie EA, Huang MT, Moore CB, Bergstralh DT, Allen IC, Lei Y, Gris D, Ting JP. J Biol Chem. 2011 Jun 3;286(22):19605-16. doi: 10.1074/jbc.M111.221077. Epub 2011 Apr 12. PubMed |
Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology. Ruan J, Shen J, Wang Z, Ji J, Song H, Wang K, Liu B, Li J, Cui D. Int J Nanomedicine. 2011;6:425-35. doi: 10.2147/IJN.S16498. Epub 2011 Feb 21. PubMed |
mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON. Li J, Liu J, Song J, Wang X, Weiss HL, Townsend CM Jr, Gao T, Evers BM. Am J Physiol Cell Physiol. 2011 Jul;301(1):C213-26. doi: 10.1152/ajpcell.00067.2011. Epub 2011 Apr 20. PubMed |
Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma. Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C. PLoS Pathog. 2011 Apr;7(4):e1002016. doi: 10.1371/journal.ppat.1002016. Epub 2011 Apr 14. PubMed |
The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9. Brockmeier U, Platzek C, Schneider K, Patak P, Bernardini A, Fandrey J, Metzen E. PLoS One. 2011 Apr 29;6(4):e19151. doi: 10.1371/journal.pone.0019151. PubMed |
Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy. Kazi AA, Hong-Brown L, Lang SM, Lang CH. Mol Med. 2011 Sep-Oct;17(9-10):925-36. doi: 10.2119/molmed.2011.00070. Epub 2011 May 19. PubMed |
Transforming growth factor beta controls CCN3 expression in nucleus pulposus cells of the intervertebral disc. Tran CM, Smith HE, Symes A, Rittie L, Perbal B, Shapiro IM, Risbud MV. Arthritis Rheum. 2011 Oct;63(10):3022-31. doi: 10.1002/art.30468. PubMed |
Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Dick E, Matsa E, Young LE, Darling D, Denning C. Nat Protoc. 2011 Jun;6(6):701-14. doi: 10.1038/nprot.2011.320. Epub 2011 May 5. PubMed |
GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release. Drabek K, van de Peppel J, Eijken M, van Leeuwen JP. J Bone Miner Res. 2011 Sep;26(9):2045-51. doi: 10.1002/jbmr.435. PubMed |
L-3-Phosphoserine phosphatase (PSPH) regulates cutaneous squamous cell carcinoma proliferation independent of L-serine biosynthesis. Bachelor MA, Lu Y, Owens DM. J Dermatol Sci. 2011 Sep;63(3):164-72. doi: 10.1016/j.jdermsci.2011.06.001. Epub 2011 Jun 22. PubMed |
Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation. Gusarova GA, Trejo HE, Dada LA, Briva A, Welch LC, Hamanaka RB, Mutlu GM, Chandel NS, Prakriya M, Sznajder JI. Mol Cell Biol. 2011 Sep;31(17):3546-56. doi: 10.1128/MCB.05114-11. Epub 2011 Jul 5. PubMed |
Lentiviral-mediated knockdown during ex vivo erythropoiesis of human hematopoietic stem cells. Palii CG, Pasha R, Brand M. J Vis Exp. 2011 Jul 16;(53). pii: 2813. doi: 10.3791/2813. PubMed |
Differentiation and neuro-protective properties of immortalized human tooth germ stem cells. Yalvac ME, Yilmaz A, Mercan D, Aydin S, Dogan A, Arslan A, Demir Z, Salafutdinov II, Shafigullina AK, Sahin F, Rizvanov AA, Palotas A. Neurochem Res. 2011 Dec;36(12):2227-35. doi: 10.1007/s11064-011-0546-7. Epub 2011 Jul 22. PubMed |
Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, Hamm LL, He X, Hervey-Jumper SL, Heth JA, Muraszko KM, DiMeco F, Vescovi AL, Fan X. Cancer Res. 2011 Sep 15;71(18):6061-72. doi: 10.1158/0008-5472.CAN-10-4269. Epub 2011 Jul 25. PubMed |
Transduction of human cells with polymer-complexed ecotropic lentivirus for enhanced biosafety. Barrilleaux B, Knoepfler P. J Vis Exp. 2011 Jul 24;(53). pii: 2822. doi: 10.3791/2822. PubMed |
Derivation of induced pluripotent stem cells by lentiviral transduction. Nethercott HE, Brick DJ, Schwartz PH. Methods Mol Biol. 2011;767:67-85. doi: 10.1007/978-1-61779-201-4_6. PubMed |
CYP2S1 and CYP2W1 mediate 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW-610, NSC 721648) sensitivity in breast and colorectal cancer cells. Tan BS, Tiong KH, Muruhadas A, Randhawa N, Choo HL, Bradshaw TD, Stevens MF, Leong CO. Mol Cancer Ther. 2011 Oct;10(10):1982-92. doi: 10.1158/1535-7163.MCT-11-0391. Epub 2011 Aug 10. PubMed |
Effect of Ser-129 phosphorylation on interaction of alpha-synuclein with synaptic and cellular membranes.
Visanji NP, Wislet-Gendebien S, Oschipok LW, Zhang G, Aubert I, Fraser PE, Tandon A.
J Biol Chem. 2011 Oct 14;286(41):35863-73. Epub 2011 Aug 17.
PubMed
Associated Plasmids |
Dickkopf-3 maintains the PANC-1 human pancreatic tumor cells in a dedifferentiated state. Zenzmaier C, Hermann M, Hengster P, Berger P. Int J Oncol. 2012 Jan;40(1):40-6. doi: 10.3892/ijo.2011.1180. Epub 2011 Aug 29. PubMed |
ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers.
Guan B, Wang TL, Shih IeM.
Cancer Res. 2011 Nov 1;71(21):6718-27. Epub 2011 Sep 7.
PubMed
Associated Plasmids |
Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors. Bandaranayake AD, Correnti C, Ryu BY, Brault M, Strong RK, Rawlings DJ. Nucleic Acids Res. 2011 Nov;39(21):e143. doi: 10.1093/nar/gkr706. Epub 2011 Sep 12. PubMed |
Modeling sarcomagenesis using multipotent mesenchymal stem cells. Rodriguez R, Rubio R, Menendez P. Cell Res. 2012 Jan;22(1):62-77. doi: 10.1038/cr.2011.157. Epub 2011 Sep 20. PubMed |
Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1. Huang S, Yang ZJ, Yu C, Sinicrope FA. J Biol Chem. 2011 Nov 18;286(46):40002-12. doi: 10.1074/jbc.M111.297432. Epub 2011 Sep 23. PubMed |
DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication. Mohni KN, Mastrocola AS, Bai P, Weller SK, Heinen CD. J Virol. 2011 Dec;85(23):12241-53. doi: 10.1128/JVI.05487-11. Epub 2011 Sep 28. PubMed |
HIF-1alpha and HIF-2alpha degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc. Fujita N, Chiba K, Shapiro IM, Risbud MV. J Bone Miner Res. 2012 Feb;27(2):401-12. doi: 10.1002/jbmr.538. PubMed |
Suppression of BCL-2 synergizes cisplatin sensitivity in nasopharyngeal carcinoma cells. Low SY, Tan BS, Choo HL, Tiong KH, Khoo AS, Leong CO. Cancer Lett. 2012 Jan 28;314(2):166-75. doi: 10.1016/j.canlet.2011.09.025. Epub 2011 Oct 8. PubMed |
Disruption of Wnt planar cell polarity signaling by aberrant accumulation of the MetAP-2 substrate Rab37. Sundberg TB, Darricarrere N, Cirone P, Li X, McDonald L, Mei X, Westlake CJ, Slusarski DC, Beynon RJ, Crews CM. Chem Biol. 2011 Oct 28;18(10):1300-11. doi: 10.1016/j.chembiol.2011.07.020. PubMed |
Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1. Orthwein A, Zahn A, Methot SP, Godin D, Conticello SG, Terada K, Di Noia JM. EMBO J. 2012 Feb 1;31(3):679-91. doi: 10.1038/emboj.2011.417. Epub 2011 Nov 15. PubMed |
FGF signalling inhibits neural induction in human embryonic stem cells. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Muller-Molina AJ, Arauzo-Bravo MJ, Han DW, Pape HC, Scholer HR. EMBO J. 2011 Nov 15;30(24):4874-84. doi: 10.1038/emboj.2011.407. PubMed |
Novel reporter systems for facile evaluation of I-SceI-mediated genome editing. Munoz NM, Beard BC, Ryu BY, Luche RM, Trobridge GD, Rawlings DJ, Scharenberg AM, Kiem HP. Nucleic Acids Res. 2012 Jan;40(2):e14. doi: 10.1093/nar/gkr897. Epub 2011 Nov 21. PubMed |
Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis. Cronan MR, Nakamura K, Johnson NL, Granger DA, Cuevas BD, Wang JG, Mackman N, Scott JE, Dohlman HG, Johnson GL. Oncogene. 2012 Aug 23;31(34):3889-900. doi: 10.1038/onc.2011.544. Epub 2011 Dec 5. PubMed |
Development of immortalized hepatocyte-like cells from hMSCs. Wongkajornsilp A, Sa-Ngiamsuntorn K, Hongeng S. Methods Mol Biol. 2012;826:73-87. doi: 10.1007/978-1-61779-468-1_7. PubMed |
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector.
Addis RC, Hsu FC, Wright RL, Dichter MA, Coulter DA, Gearhart JD.
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PKCzeta and PKMzeta are overexpressed in TCF3-rearranged paediatric acute lymphoblastic leukaemia and are associated with increased thiopurine sensitivity. Hartsink-Segers SA, Beaudoin JJ, Luijendijk MW, Exalto C, Pieters R, Den Boer ML. Leukemia. 2015 Feb;29(2):304-11. doi: 10.1038/leu.2014.210. Epub 2014 Jul 3. PubMed |
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Tumor necrosis factor-alpha- and interleukin-1beta-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-kappaB axis: implications in inflammatory disc disease. Wang X, Wang H, Yang H, Li J, Cai Q, Shapiro IM, Risbud MV. Am J Pathol. 2014 Sep;184(9):2560-72. doi: 10.1016/j.ajpath.2014.06.006. Epub 2014 Jul 22. PubMed |
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SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma. Siegle JM, Basin A, Sastre-Perona A, Yonekubo Y, Brown J, Sennett R, Rendl M, Tsirigos A, Carucci JA, Schober M. Nat Commun. 2014 Jul 31;5:4511. doi: 10.1038/ncomms5511. PubMed |
An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety. Li XF, Lytton J. J Biol Chem. 2014 Sep 12;289(37):25445-59. doi: 10.1074/jbc.M114.564450. Epub 2014 Aug 5. PubMed |
Porcine reproductive and respiratory syndrome virus counteracts the porcine intrinsic virus restriction factors-IFITM1 and Tetherin in MARC-145 cells. Wang X, Li C, Zhou L, Zhang N, Wang X, Ge X, Guo X, Yang H. Virus Res. 2014 Oct 13;191:92-100. doi: 10.1016/j.virusres.2014.07.025. Epub 2014 Aug 4. PubMed |
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Myeloid-specific disruption of tyrosine phosphatase Shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis. Tao B, Jin W, Xu J, Liang Z, Yao J, Zhang Y, Wang K, Cheng H, Zhang X, Ke Y. J Immunol. 2014 Sep 15;193(6):2801-11. doi: 10.4049/jimmunol.1303463. Epub 2014 Aug 15. PubMed |
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Human somatic cell mutagenesis creates genetically tractable sarcomas. Molyneux SD, Waterhouse PD, Shelton D, Shao YW, Watling CM, Tang QL, Harris IS, Dickson BC, Tharmapalan P, Sandve GK, Zhang X, Bailey SD, Berman H, Wunder JS, Izsvak Z, Lupien M, Mak TW, Khokha R. Nat Genet. 2014 Sep;46(9):964-72. doi: 10.1038/ng.3065. Epub 2014 Aug 17. PubMed |
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Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression. Csiszar A, Kutay B, Wirth S, Schmidt U, Macho-Maschler S, Schreiber M, Alacakaptan M, Vogel GF, Aumayr K, Huber LA, Beug H. Breast Cancer Res. 2014 Sep 9;16(5):433. doi: 10.1186/s13058-014-0433-7. PubMed |
CERS2 suppresses tumor cell invasion and is associated with decreased V-ATPase and MMP-2/MMP-9 activities in breast cancer. Fan SH, Wang YY, Lu J, Zheng YL, Wu DM, Zhang ZF, Shan Q, Hu B, Li MQ, Cheng W. J Cell Biochem. 2015 Apr;116(4):502-13. doi: 10.1002/jcb.24978. PubMed |
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Activation of the RIG-I pathway during influenza vaccination enhances the germinal center reaction, promotes T follicular helper cell induction, and provides a dose-sparing effect and protective immunity. Kulkarni RR, Rasheed MA, Bhaumik SK, Ranjan P, Cao W, Davis C, Marisetti K, Thomas S, Gangappa S, Sambhara S, Murali-Krishna K. J Virol. 2014 Dec;88(24):13990-4001. doi: 10.1128/JVI.02273-14. Epub 2014 Sep 24. PubMed |
Bortezomib sensitizes primary meningioma cells to TRAIL-induced apoptosis by enhancing formation of the death-inducing signaling complex. Koschny R, Boehm C, Sprick MR, Haas TL, Holland H, Xu LX, Krupp W, Mueller WC, Bauer M, Koschny T, Keller M, Sinn P, Meixensberger J, Walczak H, Ganten TM. J Neuropathol Exp Neurol. 2014 Nov;73(11):1034-46. doi: 10.1097/NEN.0000000000000129. PubMed |
A PTCH1 homolog transcriptionally activated by p53 suppresses Hedgehog signaling. Chung JH, Larsen AR, Chen E, Bunz F. J Biol Chem. 2014 Nov 21;289(47):33020-31. doi: 10.1074/jbc.M114.597203. Epub 2014 Oct 8. PubMed |
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Vascular channels formed by subpopulations of PECAM1+ melanoma cells. Dunleavey JM, Xiao L, Thompson J, Kim MM, Shields JM, Shelton SE, Irvin DM, Brings VE, Ollila DW, Brekken RA, Dayton PA, Melero-Martin JM, Dudley AC. Nat Commun. 2014 Oct 22;5:5200. doi: 10.1038/ncomms6200. PubMed |
Robo4 vaccines induce antibodies that retard tumor growth. Zhuang X, Ahmed F, Zhang Y, Ferguson HJ, Steele JC, Steven NM, Nagy Z, Heath VL, Toellner KM, Bicknell R. Angiogenesis. 2015 Jan;18(1):83-95. doi: 10.1007/s10456-014-9448-z. Epub 2014 Oct 28. PubMed |
Functional analysis of prognostic gene expression network genes in metastatic breast cancer models. Geiger TR, Ha NH, Faraji F, Michael HT, Rodriguez L, Walker RC, Green JE, Simpson RM, Hunter KW. PLoS One. 2014 Nov 4;9(11):e111813. doi: 10.1371/journal.pone.0111813. eCollection 2014. PubMed |
The protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicity. Chang KE, Wei BR, Madigan JP, Hall MD, Simpson RM, Zhuang Z, Gottesman MM. Mol Cancer Ther. 2015 Jan;14(1):90-100. doi: 10.1158/1535-7163.MCT-14-0496. Epub 2014 Nov 5. PubMed |
The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes. Wennmann DO, Vollenbroker B, Eckart AK, Bonse J, Erdmann F, Wolters DA, Schenk LK, Schulze U, Kremerskothen J, Weide T, Pavenstadt H. Cell Death Dis. 2014 Nov 13;5:e1519. doi: 10.1038/cddis.2014.476. PubMed |
Stable suppression of myostatin gene expression in goat fetal fibroblast cells by lentiviral vector-mediated RNAi. Patel UA, Patel AK, Joshi CG. Biotechnol Prog. 2015 Mar;31(2):452-9. doi: 10.1002/btpr.2022. Epub 2014 Nov 24. PubMed |
Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL. Ahmad K, Katryniok C, Scholz B, Merkens J, Loscher D, Marschalek R, Steinhilber D. Oncogenesis. 2014 Nov 17;3:e127. doi: 10.1038/oncsis.2014.39. PubMed |
MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL. Landon AL, Muniandy PA, Shetty AC, Lehrmann E, Volpon L, Houng S, Zhang Y, Dai B, Peroutka R, Mazan-Mamczarz K, Steinhardt J, Mahurkar A, Becker KG, Borden KL, Gartenhaus RB. Nat Commun. 2014 Nov 18;5:5413. doi: 10.1038/ncomms6413. PubMed |
Silencing long noncoding RNAs with genome-editing tools. Gutschner T. Methods Mol Biol. 2015;1239:241-50. doi: 10.1007/978-1-4939-1862-1_13. PubMed |
Andes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis. Wang Z, Mir MA. J Virol. 2015 Feb;89(3):1628-39. doi: 10.1128/JVI.02347-14. Epub 2014 Nov 19. PubMed |
Prediction and quantification of bioactive microbiota metabolites in the mouse gut. Sridharan GV, Choi K, Klemashevich C, Wu C, Prabakaran D, Pan LB, Steinmeyer S, Mueller C, Yousofshahi M, Alaniz RC, Lee K, Jayaraman A. Nat Commun. 2014 Nov 20;5:5492. doi: 10.1038/ncomms6492. PubMed |
Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers. Lefort S, Joffre C, Kieffer Y, Givel AM, Bourachot B, Zago G, Bieche I, Dubois T, Meseure D, Vincent-Salomon A, Camonis J, Mechta-Grigoriou F. Autophagy. 2014;10(12):2122-42. doi: 10.4161/15548627.2014.981788. PubMed |
Mitochondrial DNA haplogroup B5 confers genetic susceptibility to Alzheimer's disease in Han Chinese. Bi R, Zhang W, Yu D, Li X, Wang HZ, Hu QX, Zhang C, Lu W, Ni J, Fang Y, Li T, Yao YG. Neurobiol Aging. 2015 Mar;36(3):1604.e7-16. doi: 10.1016/j.neurobiolaging.2014.10.009. Epub 2014 Oct 22. PubMed |
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Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor alpha and IL-1beta in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3. Ye W, Zhou J, Markova DZ, Tian Y, Li J, Anderson DG, Shapiro IM, Risbud MV. Am J Pathol. 2015 Feb;185(2):485-95. doi: 10.1016/j.ajpath.2014.09.021. Epub 2014 Dec 2. PubMed |
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1. Duan L, Perez RE, Hansen M, Gitelis S, Maki CG. Cancer Biol Ther. 2014;15(12):1600-12. doi: 10.4161/15384047.2014.961876. PubMed |
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. Mitter SK, Song C, Qi X, Mao H, Rao H, Akin D, Lewin A, Grant M, Dunn W Jr, Ding J, Bowes Rickman C, Boulton M. Autophagy. 2014;10(11):1989-2005. doi: 10.4161/auto.36184. PubMed |
c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity. Socodato R, Portugal CC, Canedo T, Domith I, Oliveira NA, Paes-de-Carvalho R, Relvas JB, Cossenza M. Free Radic Biol Med. 2015 Feb;79:45-55. doi: 10.1016/j.freeradbiomed.2014.11.019. Epub 2014 Dec 5. PubMed |
The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes. Guo BB, Bellingham SA, Hill AF. J Biol Chem. 2015 Feb 6;290(6):3455-67. doi: 10.1074/jbc.M114.605253. Epub 2014 Dec 10. PubMed |
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Parkinson-causing alpha-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation. Dettmer U, Newman AJ, Soldner F, Luth ES, Kim NC, von Saucken VE, Sanderson JB, Jaenisch R, Bartels T, Selkoe D. Nat Commun. 2015 Jun 16;6:7314. doi: 10.1038/ncomms8314. PubMed |
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Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Panneer Selvam S, De Palma RM, Oaks JJ, Oleinik N, Peterson YK, Stahelin RV, Skordalakes E, Ponnusamy S, Garrett-Mayer E, Smith CD, Ogretmen B. Sci Signal. 2015 Jun 16;8(381):ra58. doi: 10.1126/scisignal.aaa4998. PubMed |
Pellino-1 positively regulates Toll-like Receptor (TLR) 2 and TLR4 signaling and is suppressed upon induction of endotoxin tolerance. Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev AE. J Biol Chem. 2015 Jun 16. pii: jbc.M115.640128. PubMed |
The ORF61 protein encoded by Simian Varicella Virus and Varicella Zoster Virus inhibits NFkappaB signaling by interfering with IkappaBalpha degradation. Whitmer T, Malouli D, Uebelhoer LS, DeFilippis VR, Fruh K, Verweij MC. J Virol. 2015 Jun 17. pii: JVI.01149-15. PubMed |
Induction of functional Brm protein from Brm knockout mice. Thompson KW, Marquez SB, Lu L, Reisman D. Oncoscience. 2015 Apr 18;2(4):349-61. eCollection 2015. PubMed |
IGF1R/IRS1 signaling confers pathogenic activity on breast tumor cells lacking REST. Meyer K, Albaugh B, Schoenike B, Roopra A. Mol Cell Biol. 2015 Jun 22. pii: MCB.01149-14. PubMed |
Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL. Souza PS, Madigan JP, Gillet JP, Kapoor K, Ambudkar SV, Maia RC, Gottesman MM, Leung Fung K. Exp Cell Res. 2015 Jun 19. pii: S0014-4827(15)30013-6. doi: 10.1016/j.yexcr.2015.06.005. PubMed |
mPGES-1 in prostate cancer controls stemness and amplifies EGFR-driven oncogenicity. Finetti F, Terzuoli E, Giachetti A, Santi R, Villari D, Hanaka H, Radmark O, Ziche M, Donnini S. Endocr Relat Cancer. 2015 Jun 25. pii: ERC-15-0277. PubMed |
Early growth response gene (EGR)-1 regulates leukotriene D4-induced cytokine transcription in Hodgkin lymphoma cells. Han H, Xue-Franzen Y, Miao X, Nagy E, Li N, Xu D, Sjoberg J, Bjorkholm M, Claesson HE. Prostaglandins Other Lipid Mediat. 2015 Jun 23. pii: S1098-8823(15)00075-1. doi: 10.1016/j.prostaglandins.2015.06.004. PubMed |
DEAD-box RNA helicase DDX23 modulates glioma malignancy via elevating miR-21 biogenesis. Yin J, Park G, Lee JE, Choi EY, Park JY, Kim TH, Park N, Jin X, Jung JE, Shin D, Hong JH, Kim H, Yoo H, Lee SH, Kim YJ, Park JB, Kim JH. Brain. 2015 Sep;138(Pt 9):2553-70. doi: 10.1093/brain/awv167. Epub 2015 Jun 29. PubMed |
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Overexpression of the MRI Reporter Genes Ferritin and Transferrin Receptor Affect Iron Homeostasis and Produce Limited Contrast in Mesenchymal Stem Cells. Pereira SM, Moss D, Williams SR, Murray P, Taylor A. Int J Mol Sci. 2015 Jul 8;16(7):15481-96. doi: 10.3390/ijms160715481. PubMed |
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks. Parnas O, Jovanovic M, Eisenhaure TM, Herbst RH, Dixit A, Ye CJ, Przybylski D, Platt RJ, Tirosh I, Sanjana NE, Shalem O, Satija R, Raychowdhury R, Mertins P, Carr SA, Zhang F, Hacohen N, Regev A. Cell. 2015 Jul 30;162(3):675-86. doi: 10.1016/j.cell.2015.06.059. Epub 2015 Jul 16. PubMed |
Spontaneous Cell Competition in Immortalized Mammalian Cell Lines. Penzo-Mendez AI, Chen YJ, Li J, Witze ES, Stanger BZ. PLoS One. 2015 Jul 22;10(7):e0132437. doi: 10.1371/journal.pone.0132437. eCollection 2015. PubMed |
Polarity Protein Scrib Facilitates Endothelial Inflammatory Signaling. Kruse C, Kurz AR, Palfi K, Humbert PO, Sperandio M, Brandes RP, Fork C, Michaelis UR. Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):1954-62. doi: 10.1161/ATVBAHA.115.305678. Epub 2015 Jul 23. PubMed |
The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1beta and NF-kappaB signaling. Trinh BQ, Barengo N, Kim SB, Lee JS, Zweidler-McKay PA, Naora H. J Cell Sci. 2015 Aug 15;128(16):3055-67. doi: 10.1242/jcs.168187. Epub 2015 Jul 24. PubMed |
The role of frataxin in doxorubicin-mediated cardiac hypertrophy. Mouli S, Nanayakkara G, AlAlasmari A, Eldoumani H, Fu X, Berlin A, Lohani M, Nie B, Arnold RD, Kavazis A, Smith F, Beyers R, Denney T, Dhanasekaran M, Zhong J, Quindry J, Amin R. Am J Physiol Heart Circ Physiol. 2015 Sep;309(5):H844-59. doi: 10.1152/ajpheart.00182.2015. Epub 2015 Jul 24. PubMed |
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.
Kim NG, Gumbiner BM.
J Cell Biol. 2015 Aug 3;210(3):503-15. doi: 10.1083/jcb.201501025. Epub 2015 Jul 27.
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alpha-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal. Laperle A, Hsiao C, Lampe M, Mortier J, Saha K, Palecek SP, Masters KS. Stem Cell Reports. 2015 Aug 11;5(2):195-206. doi: 10.1016/j.stemcr.2015.06.009. Epub 2015 Jul 30. PubMed |
Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression.
Barger CJ, Zhang W, Hillman J, Stablewski AB, Higgins MJ, Vanderhyden BC, Odunsi K, Karpf AR.
Oncotarget. 2015 Jul 16.
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The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism. Zaanan A, Okamoto K, Kawakami H, Khazaie K, Huang S, Sinicrope FA. J Biol Chem. 2015 Sep 25;290(39):23838-49. doi: 10.1074/jbc.M115.657833. Epub 2015 Aug 5. PubMed |
Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity. Voon YL, Ahmad M, Wong PF, Husaini R, Ng WT, Leong CO, Lane DP, Khoo AS. Oncol Rep. 2015 Oct;34(4):1692-700. doi: 10.3892/or.2015.4177. Epub 2015 Aug 5. PubMed |
CFTR inactivation by lentiviral vector-mediated RNA interference and CRISPR-Cas9 genome editing in human airway epithelial cells. Bellec J, Bacchetta M, Losa D, Anegon I, Chanson M, Nguyen TH. Curr Gene Ther. 2015;15(5):447-59. PubMed |
Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling. Archibald A, Al-Masri M, Liew-Spilger A, McCaffrey L. Mol Biol Cell. 2015 Oct 15;26(20):3578-95. doi: 10.1091/mbc.E15-05-0265. Epub 2015 Aug 12. PubMed |
Mucosally transplanted mesenchymal stem cells stimulate intestinal healing by promoting angiogenesis. Manieri NA, Mack MR, Himmelrich MD, Worthley DL, Hanson EM, Eckmann L, Wang TC, Stappenbeck TS. J Clin Invest. 2015 Sep;125(9):3606-18. doi: 10.1172/JCI81423. Epub 2015 Aug 17. PubMed |
hVGAT-mCherry: A novel molecular tool for analysis of GABAergic neurons derived from human pluripotent stem cells. DeRosa BA, Belle KC, Thomas BJ, Cukier HN, Pericak-Vance MA, Vance JM, Dykxhoorn DM. Mol Cell Neurosci. 2015 Sep;68:244-57. doi: 10.1016/j.mcn.2015.08.007. Epub 2015 Aug 16. PubMed |
Antisense-miR-21 enhances differentiation/apoptosis and reduces cancer stemness state on anaplastic thyroid cancer. Haghpanah V, Fallah P, Tavakoli R, Naderi M, Samimi H, Soleimani M, Larijani B. Tumour Biol. 2015 Aug 20. PubMed |
Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer. Komatsubara AT, Matsuda M, Aoki K. Sci Rep. 2015 Aug 20;5:13283. doi: 10.1038/srep13283. PubMed |
Retroviral Transduction of T Cells and T Cell Precursors. Simmons A, Alberola-Ila J. Methods Mol Biol. 2016;1323:99-108. doi: 10.1007/978-1-4939-2809-5_8. PubMed |
Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells. Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, Lung ML. Gastroenterology. 2015 Dec;149(7):1825-1836.e5. doi: 10.1053/j.gastro.2015.08.025. Epub 2015 Aug 22. PubMed |
JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. Tuncay H, Brinkmann BF, Steinbacher T, Schurmann A, Gerke V, Iden S, Ebnet K. Nat Commun. 2015 Aug 26;6:8128. doi: 10.1038/ncomms9128. PubMed |
CD45+ Cells Present Within Mesenchymal Stem Cell Populations Affect Network Formation of Blood-Derived Endothelial Outgrowth Cells. Peters EB, Christoforou N, Moore E, West JL, Truskey GA. Biores Open Access. 2015 Jan 1;4(1):75-88. doi: 10.1089/biores.2014.0029. eCollection 2015. PubMed |
Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling. Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE. J Leukoc Biol. 2015 Dec;98(6):963-74. doi: 10.1189/jlb.2VMA0515-229RR. Epub 2015 Aug 26. PubMed |
Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma. Rad A, Farshchian M, Forghanifard MM, Matin MM, Bahrami AR, Geerts D, A'rabi A, Memar B, Abbaszadegan MR. Tumour Biol. 2015 Aug 28. PubMed |
Derivation of LIF-independent mouse iPS cells with modified Oct4. Hirai H, Firpo M, Kikyo N. Stem Cell Res. 2015 Sep;15(2):384-6. doi: 10.1016/j.scr.2015.08.005. Epub 2015 Aug 17. PubMed |
Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining. Beckta JM, Dever SM, Gnawali N, Khalil A, Sule A, Golding SE, Rosenberg E, Narayanan A, Kehn-Hall K, Xu B, Povirk LF, Valerie K. Oncotarget. 2015 Sep 29;6(29):27674-87. doi: 10.18632/oncotarget.4876. PubMed |
Asporin Is a Fibroblast-Derived TGF-beta1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. Maris P, Blomme A, Palacios AP, Costanza B, Bellahcene A, Bianchi E, Gofflot S, Drion P, Trombino GE, Di Valentin E, Cusumano PG, Maweja S, Jerusalem G, Delvenne P, Lifrange E, Castronovo V, Turtoi A. PLoS Med. 2015 Sep 1;12(9):e1001871. doi: 10.1371/journal.pmed.1001871. eCollection 2015 Sep. PubMed |
p53-regulated autophagy is controlled by glycolysis and determines cell fate. Duan L, Perez RE, Davaadelger B, Dedkova EN, Blatter LA, Maki CG. Oncotarget. 2015 Sep 15;6(27):23135-56. PubMed |
Identification of an oncogenic RAB protein.
Wheeler DB, Zoncu R, Root DE, Sabatini DM, Sawyers CL.
Science. 2015 Oct 9;350(6257):211-7. doi: 10.1126/science.aaa4903. Epub 2015 Sep 3.
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Release of Vesicular Stomatitis Virus Spike Protein G-Pseudotyped Lentivirus from the Host Cell Is Impaired upon Low-Density Lipoprotein Receptor Overexpression. Otahal A, Fuchs R, Al-Allaf FA, Blaas D. J Virol. 2015 Nov;89(22):11723-6. doi: 10.1128/JVI.01869-15. Epub 2015 Sep 2. PubMed |
Use of genetically-encoded calcium indicators for live cell calcium imaging and localization in virus-infected cells. Perry JL, Ramachandran NK, Utama B, Hyser JM. Methods. 2015 Nov 15;90:28-38. doi: 10.1016/j.ymeth.2015.09.004. Epub 2015 Sep 3. PubMed |
Transcriptome Profiling Reveals Degree of Variability in Induced Pluripotent Stem Cell Lines: Impact for Human Disease Modeling. Schuster J, Halvardson J, Pilar Lorenzo L, Ameur A, Sobol M, Raykova D, Anneren G, Feuk L, Dahl N. Cell Reprogram. 2015 Oct;17(5):327-37. doi: 10.1089/cell.2015.0009. Epub 2015 Sep 8. PubMed |
The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry. Narayana SK, Helbig KJ, McCartney EM, Eyre NS, Bull RA, Eltahla A, Lloyd AR, Beard MR. J Biol Chem. 2015 Oct 23;290(43):25946-59. doi: 10.1074/jbc.M115.657346. Epub 2015 Sep 9. PubMed |
CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection. Wollebo HS, Bellizzi A, Kaminski R, Hu W, White MK, Khalili K. PLoS One. 2015 Sep 11;10(9):e0136046. doi: 10.1371/journal.pone.0136046. eCollection 2015. PubMed |
Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres. Schnerch D, Nigg EA. Oncogene. 2015 Sep 14. doi: 10.1038/onc.2015.332. PubMed |
The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis. Chapard C, Hohl D, Huber M. Oncotarget. 2015 Aug 28;6(25):20933-45. PubMed |
Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2. Martin KA, Cesaroni M, Denny MF, Lupey LN, Tempera I. Mol Cell Biol. 2015 Dec;35(23):3934-44. doi: 10.1128/MCB.00635-15. Epub 2015 Sep 14. PubMed |
MicroRNA-based conversion of human fibroblasts into striatal medium spiny neurons.
Richner M, Victor MB, Liu Y, Abernathy D, Yoo AS.
Nat Protoc. 2015 Oct;10(10):1543-55. doi: 10.1038/nprot.2015.102. Epub 2015 Sep 17.
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Associated Plasmids |
Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in culture. Jonsdottir HR, Arason AJ, Palsson R, Franzdottir SR, Gudbjartsson T, Isaksson HJ, Gudmundsson G, Gudjonsson T, Magnusson MK. Lab Invest. 2015 Dec;95(12):1418-28. doi: 10.1038/labinvest.2015.114. Epub 2015 Sep 21. PubMed |
Routes of Ca2+ Shuttling during Ca2+ Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca2+ HANDLING AND CYTOSOLIC Ca2+ BUFFERS. Pecze L, Blum W, Schwaller B. J Biol Chem. 2015 Nov 20;290(47):28214-30. doi: 10.1074/jbc.M115.663179. Epub 2015 Sep 22. PubMed |
OTX2 is a therapeutic target for retinoblastoma and may function as a common factor between C-MYC, CRX, and phosphorylated RB pathways. Li J, Di C, Jing J, Di Q, Nakhla J, Adamson DC. Int J Oncol. 2015 Nov;47(5):1703-10. doi: 10.3892/ijo.2015.3179. Epub 2015 Sep 23. PubMed |
Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts.
Kubaczka C, Senner CE, Cierlitza M, Arauzo-Bravo MJ, Kuckenberg P, Peitz M, Hemberger M, Schorle H.
Cell Stem Cell. 2015 Sep 22. pii: S1934-5909(15)00360-4. doi: 10.1016/j.stem.2015.08.005.
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Associated Plasmids |
LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment. Pena CG, Nakada Y, Saatcioglu HD, Aloisio GM, Cuevas I, Zhang S, Miller DS, Lea JS, Wong KK, DeBerardinis RJ, Amelio AL, Brekken RA, Castrillon DH. J Clin Invest. 2015 Nov 2;125(11):4063-76. doi: 10.1172/JCI82152. Epub 2015 Sep 28. PubMed |
EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF. Chen Y, Gou X, Kong DK, Wang X, Wang J, Chen Z, Huang C, Zhou J. Oncotarget. 2015 Oct 20;6(32):32575-85. doi: 10.18632/oncotarget.5331. PubMed |
ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells. Zhu P, Wang Y, He L, Huang G, Du Y, Zhang G, Yan X, Xia P, Ye B, Wang S, Hao L, Wu J, Fan Z. J Clin Invest. 2015 Oct 1;125(10):3795-808. doi: 10.1172/JCI81979. Epub 2015 Aug 31. PubMed |
Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells. Nawandar DM, Wang A, Makielski K, Lee D, Ma S, Barlow E, Reusch J, Jiang R, Wille CK, Greenspan D, Greenspan JS, Mertz JE, Hutt-Fletcher L, Johannsen EC, Lambert PF, Kenney SC. PLoS Pathog. 2015 Oct 2;11(10):e1005195. doi: 10.1371/journal.ppat.1005195. eCollection 2015 Oct. PubMed |
Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome. Piroli GG, Manuel AM, Clapper AC, Walla MD, Baatz JE, Palmiter RD, Quintana A, Frizzell N. Mol Cell Proteomics. 2016 Feb;15(2):445-61. doi: 10.1074/mcp.M115.051516. Epub 2015 Oct 8. PubMed |
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation. Tan Y, AlKhamees B, Jia D, Li L, Couture JF, Figeys D, Jinushi M, Wang L. Stem Cell Reports. 2015 Nov 10;5(5):741-52. doi: 10.1016/j.stemcr.2015.09.005. Epub 2015 Oct 8. PubMed |
Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth. Vallabhapurapu SD, Noothi SK, Pullum DA, Lawrie CH, Pallapati R, Potluri V, Kuntzen C, Khan S, Plas DR, Orlowski RZ, Chesi M, Kuehl WM, Bergsagel PL, Karin M, Vallabhapurapu S. Nat Commun. 2015 Oct 12;6:8428. doi: 10.1038/ncomms9428. PubMed |
Reliable and inexpensive expression of large, tagged, exogenous proteins in murine bone marrow-derived macrophages using a second generation lentiviral system. Miller MR, Blystone SD. J Biol Methods. 2015;2(3):e23. PubMed |
MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma. Lee JS, Tang SS, Ortiz V, Vo TT, Fruman DA. Oncotarget. 2015 Nov 3;6(34):35202-17. doi: 10.18632/oncotarget.6051. PubMed |
Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma. Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, Prukova D, Vejmelkova D, Jaksa R, Helman K, Vockova P, Lateckova L, Molinsky J, Maswabi BC, Alam M, Kodet R, Pytlik R, Trneny M, Klener P. Clin Cancer Res. 2015 Oct 14. PubMed |
The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization. Rohrbach TD, Shah N, Jackson WP, Feeney EV, Scanlon S, Gish R, Khodadadi R, Hyde SO, Hicks PH, Anderson JC, Jarboe JS, Willey CD. PLoS One. 2015 Oct 15;10(10):e0140870. doi: 10.1371/journal.pone.0140870. eCollection 2015. PubMed |
Knockdown of GLP-1 Receptors in Vagal Afferents Affects Normal Food Intake and Glycemia. Krieger JP, Arnold M, Pettersen KG, Lossel P, Langhans W, Lee SJ. Diabetes. 2016 Jan;65(1):34-43. doi: 10.2337/db15-0973. Epub 2015 Oct 15. PubMed |
Targeting mitochondrial RNA polymerase in acute myeloid leukemia. Bralha FN, Liyanage SU, Hurren R, Wang X, Son MH, Fung TA, Chingcuanco FB, Tung AY, Andreazza AC, Psarianos P, Schimmer AD, Salmena L, Laposa RR. Oncotarget. 2015 Nov 10;6(35):37216-28. doi: 10.18632/oncotarget.6129. PubMed |
Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 Proteins. Habiger C, Jager G, Walter M, Iftner T, Stubenrauch F. J Virol. 2015 Oct 21;90(2):694-704. doi: 10.1128/JVI.02137-15. PubMed |
DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAs.
Aparicio-Prat E, Arnan C, Sala I, Bosch N, Guigo R, Johnson R.
BMC Genomics. 2015 Oct 23;16(1):846. doi: 10.1186/s12864-015-2086-z.
PubMed
Associated Plasmids |
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA.
Nat Methods. 2015 Dec;12(12):1143-9. doi: 10.1038/nmeth.3630. Epub 2015 Oct 26.
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Associated Plasmids |
Skeletal Muscle Phospholipid Metabolism Regulates Insulin Sensitivity and Contractile Function. Funai K, Lodhi IJ, Spears LD, Yin L, Song H, Klein S, Semenkovich CF. Diabetes. 2016 Feb;65(2):358-70. doi: 10.2337/db15-0659. Epub 2015 Oct 28. PubMed |
Identification of short-form RON as a novel intrinsic resistance mechanism for anti-MET therapy in MET-positive gastric cancer. Wu Z, Zhang Z, Ge X, Lin Y, Dai C, Chang J, Liu X, Geng R, Wang C, Chen H, Sun M, Guo W, Li J. Oncotarget. 2015 Dec 1;6(38):40519-34. doi: 10.18632/oncotarget.5816. PubMed |
Combinatorial BTK and MALT1 inhibition augments killing of CD79 mutant diffuse large B cell lymphoma. Nagel D, Bognar M, Eitelhuber AC, Kutzner K, Vincendeau M, Krappmann D. Oncotarget. 2015 Dec 8;6(39):42232-42. doi: 10.18632/oncotarget.6273. PubMed |
The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Baskin JM, Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, Reinisch KM, De Camilli P. Nat Cell Biol. 2016 Jan;18(1):132-8. doi: 10.1038/ncb3271. Epub 2015 Nov 16. PubMed |
Fat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cells. Ma L, Cui J, Xi H, Bian S, Wei B, Chen L. Cancer Biol Ther. 2016;17(1):36-47. doi: 10.1080/15384047.2015.1108488. PubMed |
ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas. Yang H, Schramek D, Adam RC, Keyes BE, Wang P, Zheng D, Fuchs E. Elife. 2015 Nov 21;4. pii: e10870. doi: 10.7554/eLife.10870. PubMed |
Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression. Ogiwara H, Sasaki M, Mitachi T, Oike T, Higuchi S, Tominaga Y, Kohno T. Cancer Discov. 2016 Apr;6(4):430-45. doi: 10.1158/2159-8290.CD-15-0754. Epub 2015 Nov 24. PubMed |
A PCR-Based Method to Construct Lentiviral Vector Expressing Double Tough Decoy for miRNA Inhibition. Qiu H, Zhong J, Luo L, Liu N, Kang K, Qu J, Peng W, Gou D. PLoS One. 2015 Dec 1;10(12):e0143864. doi: 10.1371/journal.pone.0143864. eCollection 2015. PubMed |
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, Wu J, Xu X, Fu L, Li Y, Yang J, Zhang W, Bai R, Yi F, Suzuki K, Gao H, Esteban CR, Zhang C, Izpisua Belmonte JC, Chen Z, Wang X, Jiang T, Qu J, Tang F, Liu GH. Nat Commun. 2015 Dec 3;6:10068. doi: 10.1038/ncomms10068. PubMed |
alpha-synuclein interacts with SOD1 and promotes its oligomerization. Helferich AM, Ruf WP, Grozdanov V, Freischmidt A, Feiler MS, Zondler L, Ludolph AC, McLean PJ, Weishaupt JH, Danzer KM. Mol Neurodegener. 2015 Dec 8;10:66. doi: 10.1186/s13024-015-0062-3. PubMed |
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, Berger H, Mollenkopf HJ, Mangler M, Sehouli J, Fotopoulou C, Meyer TF. Nat Commun. 2015 Dec 8;6:8989. doi: 10.1038/ncomms9989. PubMed |
Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets. Morris VA, Cummings CL, Korb B, Boaglio S, Oehler VG. Mol Cell Biol. 2015 Dec 7;36(4):559-73. doi: 10.1128/MCB.00712-15. PubMed |
A Common CCK-B Receptor Intronic Variant in Pancreatic Adenocarcinoma in a Hungarian Cohort. Balazs A, Nemeth BC, Ordog B, Hegyi E, Hritz I, Czako L, Czimmer J, Godi S, Csiszko A, Rakonczay Z Jr, Parniczky A, Izbeki F, Halasz A, Kahan Z, Hegyi P, Sahin-Toth M. Pancreas. 2016 Apr;45(4):541-5. doi: 10.1097/MPA.0000000000000539. PubMed |
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. Sali TM, Pryke KM, Abraham J, Liu A, Archer I, Broeckel R, Staverosky JA, Smith JL, Al-Shammari A, Amsler L, Sheridan K, Nilsen A, Streblow DN, DeFilippis VR. PLoS Pathog. 2015 Dec 8;11(12):e1005324. doi: 10.1371/journal.ppat.1005324. eCollection 2015 Dec. PubMed |
A new design of a lentiviral shRNA vector with inducible co-expression of ARGONAUTE 2 for enhancing gene silencing efficiency. He J, Huang L, Qiu H, Li J, Luo L, Li Y, Tian S, Kang K, Luo J, Liu L, Gou D. Cell Biosci. 2015 Dec 8;5:67. doi: 10.1186/s13578-015-0058-2. eCollection 2015. PubMed |
A Gene Expression Signature Associated with Overall Survival in Patients with Hepatocellular Carcinoma Suggests a New Treatment Strategy. Gillet JP, Andersen JB, Madigan JP, Varma S, Bagni RK, Powell K, Burgan WE, Wu CP, Calcagno AM, Ambudkar SV, Thorgeirsson SS, Gottesman MM. Mol Pharmacol. 2016 Feb;89(2):263-72. doi: 10.1124/mol.115.101360. Epub 2015 Dec 14. PubMed |
TBX3 Knockdown Decreases Reprogramming Efficiency of Human Cells. Klingenstein M, Raab S, Achberger K, Kleger A, Liebau S, Linta L. Stem Cells Int. 2016;2016:6759343. doi: 10.1155/2016/6759343. Epub 2015 Nov 30. PubMed |
Upregulation of EMMPRIN (OX47) in Rat Dorsal Root Ganglion Contributes to the Development of Mechanical Allodynia after Nerve Injury. Wang Q, Sun Y, Ren Y, Gao Y, Tian L, Liu Y, Pu Y, Gou X, Chen Y, Lu Y. Neural Plast. 2015;2015:249756. doi: 10.1155/2015/249756. Epub 2015 Nov 30. PubMed |
Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential. Ferre CA, Davezac N, Thouard A, Peyrin JM, Belenguer P, Miquel MC, Gonzalez-Dunia D, Szelechowski M. FASEB J. 2015 Dec 23. pii: fj.15-279620. PubMed |
Ebola virus mediated infectivity is restricted in canine and feline cells. Han Z, Bart SM, Ruthel G, Vande Burgt NH, Haines KM, Volk SW, Vite CH, Freedman BD, Bates P, Harty RN. Vet Microbiol. 2016 Jan 15;182:102-7. doi: 10.1016/j.vetmic.2015.11.011. Epub 2015 Nov 17. PubMed |
Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes. Raab JR, Resnick S, Magnuson T. PLoS Genet. 2015 Dec 30;11(12):e1005748. doi: 10.1371/journal.pgen.1005748. eCollection 2015 Dec. PubMed |
NIPBL Controls RNA Biogenesis to Prevent Activation of the Stress Kinase PKR. Yuen KC, Xu B, Krantz ID, Gerton JL. Cell Rep. 2016 Jan 5;14(1):93-102. doi: 10.1016/j.celrep.2015.12.012. Epub 2015 Dec 24. PubMed |
The Polymerase Activity of Mammalian DNA Pol zeta Is Specifically Required for Cell and Embryonic Viability. Lange SS, Tomida J, Boulware KS, Bhetawal S, Wood RD. PLoS Genet. 2016 Jan 4;12(1):e1005759. doi: 10.1371/journal.pgen.1005759. eCollection 2016 Jan. PubMed |
Inhibition of Canonical NF-kappaB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction. Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D. Sci Rep. 2016 Jan 7;6:18934. doi: 10.1038/srep18934. PubMed |
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Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. Lalli MA, Jang J, Park JC, Wang Y, Guzman E, Zhou H, Audouard M, Bridges D, Tovar KR, Papuc SM, Tutulan-Cunita AC, Huang Y, Budisteanu M, Arghir A, Kosik KS. Hum Mol Genet. 2016 Jan 10. pii: ddw010. PubMed |
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